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Deaths involving the opioid painkiller fentanyl more than doubled from 2013 to 2014, according to a report released by the Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS). The report provides a detailed picture of the drugs most frequently involved in drug overdose deaths in the United States and highlights the frequency of […]
Read MoreAuthors: R. L. Johnson et al Br J Anaesth. 2016;116(2):163-176. A Systematic Review of Comparative-Effectiveness Research Background: This systematic review evaluated the evidence comparing patient-important outcomes in spinal or epidural vs general anaesthesia for total hip and total knee arthroplasty. Methods: MEDLINE, Ovid EMBASE, EBSCO CINAHL, Thomson Reuters Web of Science, and the Cochrane Central Register of Controlled Trials from […]
Read MoreRepeated or lengthy use of general anesthetic and sedation drugs in infants, toddlers and pregnant women in their third trimester might damage children’s developing brains, the U.S. Food and Drug Administration warned this month. Upset that the warning about pregnant women was based solely on animal studies, the American College of Obstetricians and Gynecologists, or […]
Read MoreBy Will Boggs MD About one in 20 patients might be aware of sensory stimuli during anesthesia, a rate lower than previously reported, according to an international, multicenter study. “We were pleased that the incidence of connected consciousness after intubation was lower than we feared, but we must be cautious, given the low event rate, […]
Read MoreAuthors: Feng Li et al BMC Anesthesiol. 2015;15(128) Background: To evaluate the cardioprotective effects of sevoflurane versus propofol anesthesia in patients undergoing cardiac surgery. Methods: Studies were retrieved through searching several databases. Study quality was evaluated by Jadad scale. Meta-analysis was performed with RevMan5.0 software. Publication bias was tested by funnel plot. Results: As a result, 15 studies were […]
Read MoreAuthors: Jonathan Yong et al Int J Qual Health Care. 2015;27(6):472-477. Objectives: The aim of this study was to identify clinical patterns of occurrence, management and outcomes surrounding cardiac arrest during laparoscopic surgery using the Australian Incident Monitoring Study (AIMS) database to guide possible prevention and treatment. Setting: The AIMS database includes incident reports from participating clinicians from […]
Read MoreRegular use of over-the-counter non-steroidal inflammatory drugs (NSAIDs) is associated with an increased risk of dying in patients diagnosed with type 1 endometrial cancers, according to a study published in the Journal of the National Cancer Institute. For the observational study, Theodore Brasky, PhD, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, and colleagues sought to […]
Read MoreAuthors: S. Weibel et al Br J Anaesth. 2016;116(6):770-783. A Systematic Review With Trial Sequential Analysis Background: Improvement of postoperative pain and other perioperative outcomes remain a significant challenge and a matter of debate among perioperative clinicians. This systematic review aims to evaluate the effects of perioperative i.v. lidocaine infusion on postoperative pain and recovery in patients […]
Read MoreFor patients with acute traumatic brain injury (TBI), the higher the prehospital systolic blood pressure the better — a finding that challenges the conventional wisdom that there is a clinically meaningful threshold, new research suggests. The study — the largest to date to look at this issue — found a linear association between lowest prehospital […]
Read MoreAUTHORS: Zaouter, Cédrick MD et al Anesthesia & Analgesia: December 2016 BACKGROUND: Recently, several trials have shown that closed-loop sedation is feasible. No study has used automated sedation in extremely frail patients, such as those scheduled for transcatheter aortic valve implantation (TAVI). We developed and tested a novel automated sedation system for this kind of population […]
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