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Authors: Gabriela A. Calhoun, M.D. et al George Washington University, Washington, Dist. of Columbia, United States Background: Ketamine has been in clinical practice since the 1960s, used for its analgesic properties as a N-methyl-d-aspartic acid receptor antagonist (1). The role of ketamine at lower, sub-anesthetic doses has recently gained interest in chronic pain management, a condition affecting […]
Read MoreAuthors: Toshiya Koitabashi, M.D.,Ph.D. et al Tokyo Dental College Ichikawa General Hospital, Koto-ku, Tokyo, Japan Introduction: Tapentadol (TP) has two mechanisms of action: mu-opioid receptor agonism and noradrenaline reuptake inhibition. Since TP has been developed for the management of chronic pain, there is paucity of information regarding the efficacy and tolerability in cancer pain management. We […]
Read MoreThere are disproportionately higher rates of in-hospital mortality, postoperative complications and hospital readmission rates after isolated coronary artery bypass graft (CABG) surgery in patients on Medicare, Medicaid and those without insurance, compared with those with private insurance. “Our anesthesiology department wants to know how anesthesia care impacts patient outcomes,” said Zachary A. Turnbull, MD, an […]
Read MoreAUTHORS: Katz, Daniel, MD et al Anesthesia & Analgesia: Oct 2017 BACKGROUND: Spinal anesthesia has become the most common type of anesthetic for cesarean delivery. The major limitation to spinal anesthesia is that the duration of the anesthetic may not be adequate in the event of a prolonged surgery. Some practitioners add epinephrine to hyperbaric bupivacaine to […]
Read MoreAlthough most of the conversation about the epidemic of prescription opioid abuse centers on chronic pain, opioids also are massively overprescribed for acute pain in children, research shows. Myron Yaster, MD, professor of anesthesiology at the University of Colorado Denver and an anesthesiologist at Children’s Hospital Colorado, in Aurora, reviewed research showing that opioids are […]
Read MoreIn patients undergoing arthroscopic hip surgery, the addition of a preoperative fascia iliaca compartment block to intra-articular local anesthetic injection showed no improvement in postoperative analgesia and resulted in leg weakness, compared with placebo. According to the researchers, these results contradict earlier reports and suggest that the fascia iliaca compartment block fails to change a patient’s pain experience due […]
Read MoreAUTHORS: Abbott, Tom E., F., MRCP et al Anesthesia & Analgesia: Oct 2017 BACKGROUND: The association between intraoperative cardiovascular changes and perioperative myocardial injury has chiefly focused on hypotension during noncardiac surgery. However, the relative influence of blood pressure and heart rate (HR) remains unclear. We investigated both individual and codependent relationships among intraoperative HR, systolic blood […]
Read MoreExtending the duration of adductor canal blocks after total knee arthroplasty may improve pain control without compromising functional outcomes or delaying discharge. Results of a prospective, randomized, open-label study show that a higher proportion of patients randomly assigned to 48-hour infusion experienced milder pain after total knee arthroplasty when compared with a single-shot injection and […]
Read MoreIntravenous (IV) oliceridine can effectively and safely help manage moderate-to-severe post-surgical pain, according to results of a phase 3 study presented at the 2017 Annual Meeting of the American Society of Anesthesiologists (ASA). Eugene R. Viscusi, MD, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, and colleagues assessed the proportion of patients who responded to […]
Read MoreWhen it comes to intubation, every second counts, and difficult airways can quickly become life-threatening situations. At Johns Hopkins Hospital, in Baltimore, any concern for a difficult airway can trigger activation of the difficult airway response team (DART), which brings together a multidisciplinary group of physicians that can quickly and effectively manage the most challenging […]
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