Authors: Beukers A et al. Anesthesia & Analgesia, Volume 142, Issue 1, pages 5–14, January 2026 Summary:This narrative review synthesizes how cardiopulmonary bypass (CPB) alters the pharmacokinetics (PK) and pharmacodynamics (PD) of commonly used continuously administered anesthetic and analgesic drugs during on-pump cardiac surgery, and why those shifts can translate into clinically meaningful under- or […]
Read MoreAuthors: Cheng S et al. Anesthesia & Analgesia, Volume 142, Issue 1, pages 19–27, January 2026 Summary:This randomized, blinded noninferiority trial evaluated whether intrathecal hydromorphone is noninferior to intrathecal morphine for postcesarean delivery analgesia when both are administered at their previously established ED90 doses. Given ongoing concerns regarding morphine-related side effects and intermittent drug shortages, […]
Read MoreAuthors: Dragovic SZ et al. Anesthesia & Analgesia, Volume 142, Issue 2, pages 249–260, February 2026 Summary:This retrospective study examines whether commonly used processed EEG metrics obscure meaningful differences between anesthetic agents, particularly propofol versus volatile fluranes (sevoflurane and desflurane). The authors challenge the “one-size-fits-all” assumption that equivalent processed EEG targets reflect comparable anesthetic brain […]
Read MoreAuthors: Kong H et al. Journal: Anesthesiology, November 25, 2025. DOI: 10.1097/ALN.0000000000005778 SummaryThis randomized, double-blind, placebo-controlled trial evaluated whether preemptive magnesium sulfate infusion improves intraoperative hemodynamic stability during pheochromocytoma and paraganglioma (PPGL) resection—procedures well known for extreme catecholamine-mediated blood pressure and heart rate fluctuations. Ninety-two patients scheduled for PPGL resection were randomized to receive either […]
Read MoreAuthor: Sophie Eydis Becker’s ASC Review Anesthesiology saw a year of significant innovation in 2025 as new technologies, techniques and care models redefined what is possible in the perioperative environment. From AI-driven automation to next-generation pain control, five breakthroughs in particular helped shape the specialty. 1. AI-driven decision support, smart ultrasound and virtual reality-enhanced training […]
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