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Dose–Response Relationship in Cardiac Surgery: Ottawa, Ontario, Canada—Cardiac anesthesiologists can add acute kidney injury (AKI) to the many deleterious effects of intraoperative hypotension. A retrospective cohort study by a team of Canadian investigators found a relationship between kidney injury and mean arterial pressure (MAP) less than 65 mm Hg, but also uncovered evidence of a […]
Read MoreThe longer a patient is in severe pain during the first 24 hours following surgery, the more likely he or she will still be experiencing some form of chronic postsurgical pain one year later, according to a study presented at Euroanaesthesia 2015. This prospective, observational study (abstract ESAPC1-2), designed to investigate the incidence, characteristics and […]
Read MoreAnesthesia & Analgesia: Sept 2015 Authors: Baeriswyl, Moira MD, et al BACKGROUND: Previous meta-analyses of the transversus abdominis plane (TAP) block have examined a maximum of 12 articles, including fewer than 650 participants, and have not examined the effect of ultrasound-guided techniques specifically. Recently, many trials that use ultrasound approaches to TAP block have been […]
Read MoreCan J Anaesth, 2015 Dec;62(12):1268-1278. Authors: Xiong C et al PURPOSE: Palonosetron, a second-generation 5-hydroxytryptamine 3 receptor antagonist (5-HT3RA), has unique characteristics relative to first-generation 5-HT3RAs such as ondansetron. Nevertheless, it remains unclear if palonosetron is better than ondansetron for the prevention of nausea and vomiting during the first 24 hr after surgery and is thus the […]
Read MoreCan J Anaesth, 2015 Nov;62(11):1169-1178. Authors: Allen M et al PURPOSE: This study aimed to determine if the incidence of recall was equivalent between light and deep sedation for colonoscopy. Secondary analysis included complications, patient clinical recovery, and post-procedure cognitive impairment. METHODS: Two hundred patients undergoing elective outpatient colonoscopy were randomized to light (bispectral index [BIS] 70-80) […]
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