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Anesthesiology 10 2016, Vol.125, 700-715 Authors: Åse Lodenius, M.D., D.E.S.A. et al Background: In contrast to general anesthetics such as propofol, dexmedetomidine when used for sedation has been put forward as a drug with minimal effects on respiration. To obtain a more comprehensive understanding of the regulation of breathing during sedation with dexmedetomidine, the authors compared ventilatory […]
Read MoreEdited by David G. Fairchild, MD, MPH Low-dose hydrocortisone infusion may not prevent progression to septic shock among adults with severe sepsis, according to a JAMA study. Some 380 adults with severe sepsis who were not in septic shock were randomized to receive placebo or hydrocortisone (an initial 50-mg intravenous bolus, followed by a 200-mg continuous infusion daily […]
Read MoreWithout these teamwork qualities, your OR staff’s pre-surgical rundowns may be incomplete. A TEAM WORKS Patient safety depends on communication and respect. Your physicians are the undisputed captains of the surgical ship, but are they totally onboard with patient safety? According to a recent study, that may require them to share leadership with their OR staff. […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 659–669 AUTHORS: Mongardon, Nicolas MD, MSc et al BACKGROUND: In animal models, whole-body cooling reduces end-organ injury after cardiac arrest and other hypoperfusion states. The benefits of cooling in humans, however, are uncertain, possibly because detrimental effects of prolonged cooling may offset […]
Read MoreAnesthesia & Analgesia: July 29, 2016 AUTHORS: Brogi, Etrusca MD et al BACKGROUND: Automated systems can improve the stability of controlled variables and reduce the workload in clinical practice without increasing the risks to patients. We conducted this review and meta-analysis to assess the clinical performance of closed-loop systems compared with manual control. Our primary […]
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