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Authors: Shiyang Li et al BMC Anesthesiol. 2016;16(24) Background: Propofol and fentanyl are the most widely administered anesthesia maintaining drugs during colonoscopy. In this study, we determined the median effective concentration (EC50) of propofol required for colonoscopy in elderly patients, and the purpose of this study was to describe the pharmacodynamic interaction between fentanyl and propofol when […]
Read MoreResearchers have determined that patients who have not had an opioid prescription within 1 year prior to their procedure are at low risk of developing persistent opioid use after major surgery. The research, published online by JAMA Surgery, showed that of the 39,140 observed patients only 0.4% (~1 in every 225 patients) continued to receive ongoing […]
Read MoreThis is for our pain docs. Using the common pain-relieving medication acetaminophen during pregnancy was associated with increased risk for multiple behavioural problems in children, according to an article published online by JAMA Pediatrics. Acetaminophen is generally considered safe in pregnancy and is used by a many pregnant women for pain and fever. Evie Stergiakouli, […]
Read MoreAnesthesia & Analgesia: August 12, 2016 AUTHORS: Liu, Jia-Ren MD, PhD et al BACKGROUND: Dexmedetomidine (DEX) has inherent neuroprotective properties that have been attributed to the activation of prosurvival kinases. However, the impact of supraclinical doses of DEX on neuroapoptosis and neuronal viability has not been determined. METHODS: Rat pups and primary neuronal cells were […]
Read MoreAnesthesia & Analgesia: Anesthesia & Analgesia: August 12, 2016 AUTHORS: Faraoni, David MD, PhD, FCCP et al BACKGROUND: Children with major and severe congenital heart disease (CHD) undergoing noncardiac surgery are at increased risk of mortality. The objective of this study was to identify the predictors for in-hospital mortality, and to develop a risk stratification […]
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