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Uncategorized Published - 27 February, 2017    By - Dr Clemens
Anesthetics, the Ryanodine Receptors, and the Heart

Authors: Ion A. Hobai, M.D., Ph.D. Anesthesiology 3 2017, Vol.126, 373-375. CARDIOVASCULAR complications are still a major cause of perioperative mortality and morbidity.1  Myocardial ischemia, arrhythmias, and cardiac pump failure usually harm patients with preexisting cardiac disease and/or during extreme hemodynamic challenges. To prevent these complications, a substantial body of research aims to understand the effects exerted […]

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Uncategorized Published - 27 February, 2017    By - Dr Clemens
Ketamine: A Drug at War with Itself

Authors: Paul Garcia, M.D., Ph.D. et al Anesthesiology 3 2017, Vol.126, 371-372. KETAMINE has always been the odd one out. Like an eccentric uncle who always turns up at the holiday season with a new partner, ketamine has never really comfortably fitted in to simple classifications of anesthetic drugs. Obviously, the anesthesia produced by ketamine is qualitatively […]

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Uncategorized Published - 27 February, 2017    By - Dr Clemens
Adjusting the Focus on Transfusion-associated Circulatory Overload

Authors: Nareg Roubinian, M.D., M.P.H.T.M. et al Anesthesiology 3 2017, Vol.126, 363-365. TRANSFUSION-ASSOCIATED circulatory overload (TACO) remains the most common pulmonary complication of transfusion and the second most common cause of transfusion-related deaths reported to the Food and Drug Administration.  The term TACO was coined by Popovsky  in 1983 and is characterized by new or worsening hydrostatic pulmonary […]

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Uncategorized Published - 27 February, 2017    By - Dr Clemens
Does a Platelet Transfusion Independently Affect Bleeding and Adverse Outcomes in Cardiac Surgery?

Authors: Fabienne M. A. van Hout et al Anesthesiology 3 2017, Vol.126, 441-449. Background: Conflicting results have been reported concerning the effect of platelet transfusion on several outcomes. The aim of this study was to assess the independent effect of a single early intraoperative platelet transfusion on bleeding and adverse outcomes in cardiac surgery patients. Methods: For this […]

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Uncategorized Published - 27 February, 2017    By - Dr Clemens
Impact of Pain on Incident Risk of Disability in Elderly Japanese: Cause-specific Analysis

Authors: Yu Kaiho, M.D. et al Anesthesiology February 16, 2017 Background: Although several cross-sectional studies have reported that pain is associated with functional disability in the elderly, data regarding a longitudinal association between pain and disability are inconsistent. This study aimed to investigate the association of pain severity with subsequent functional disability due to all causes as […]

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