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Uncategorized Published - 18 September, 2017    By - Dr Clemens
Investigation of Slow-wave Activity Saturation during Surgical Anesthesia Reveals a Signature of Neural Inertia in Humans

Authors: Catherine E. Warnaby, Ph.D. et al Anesthesiology 10 2017, Vol.127, 645-657. Background: Previously, we showed experimentally that saturation of slow-wave activity provides a potentially individualized neurophysiologic endpoint for perception loss during anesthesia. Furthermore, it is clear that induction and emergence from anesthesia are not symmetrically reversible processes. The observed hysteresis is potentially underpinned by a neural […]

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Uncategorized Published - 18 September, 2017    By - Dr Clemens
Epidural Labor Analgesia—Fentanyl Dose and Breastfeeding Success: A Randomized Clinical Trial

Authors: Amy I. Lee, M.D. et al Anesthesiology 10 2017, Vol.127, 614-624. Background: Breastfeeding is an important public health concern. High cumulative doses of epidural fentanyl administered for labor analgesia have been reported to be associated with early termination of breastfeeding. We tested the hypothesis that breastfeeding success is adversely influenced by the cumulative epidural fentanyl dose […]

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Uncategorized Published - 15 September, 2017    By - Dr Clemens
Factors Influencing Quality of Pain Management in a Physician Staffed Helicopter Emergency Medical Service

AUTHORS: Oberholzer, Nicole CM et al Anesthesia & Analgesia: July 2017 – Volume 125 – Issue 1 – p 200–209 BACKGROUND: Pain is frequently encountered in the prehospital setting and needs to be treated quickly and sufficiently. However, incidences of insufficient analgesia after prehospital treatment by emergency medical services are reported to be as high as […]

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Uncategorized Published - 15 September, 2017    By - Dr Clemens
Pupillary Reflex for Evaluation of Thoracic Paravertebral Block: A Prospective Observational Feasibility Study.

AUTHORS: Duceau, Baptiste MD et al Anesthesia & Analgesia: May 4, 2017 BACKGROUND: Although thoracic paravertebral block (TPVB) is recommended in major breast surgery, there is no gold standard to assess the success of TPVB. Pupillary dilation reflex (PDR) is the variation of the pupillary diameter after a noxious stimulus. The objective was to evaluate the […]

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Uncategorized Published - 15 September, 2017    By - Dr Clemens
Differences in Blood Pressure in Infants After General Anesthesia Compared to Awake Regional Anesthesia (GAS Study—A Prospective Randomized Trial)

AUTHORS: McCann, M. E. MD, MPH et al Anesthesia & Analgesia: September 2017 – Volume 125 – Issue 3 – p 837–845 BACKGROUND: The General Anesthesia compared to Spinal anesthesia (GAS) study is a prospective randomized, controlled, multisite, trial designed to assess the influence of general anesthesia (GA) on neurodevelopment at 5 years of age. A […]

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