The optimal range of fluid administration in patients undergoing lung resection surgery has been a controversial topic in anesthesia. There are hazards at both ends of the spectrum: Liberal overhydration can lead to fluid-induced lung injury, while conservative fluid-management strategies have a risk for organ ischemia.
“We’ve come a long way since post–lung resection lung injury was first described in 1984,” said Dr. Lohser. “We now realize that there are a vast number of factors that affect the ventilated lung and the collapsed lung. … What hasn’t changed is that acute lung injury remains the leading cause of death post–lung resection.”
On the other end of the spectrum, fluid restriction raises the “specter of organ malperfusion,” Dr. Lohser pointed out.