Magnesium sulfate reduces postoperative pain in women with cesarean section

DG Journal Clubs
AUTHORS: Siguang Ma, Yanju Zhang et al.
Pain Pract. 2022 Jan; 22(1): 8-18

OBJECTIVES The use of magnesium sulfate (MgSO 4 ) as an adjunct in different anesthetic regimens for cesarean section (CS) delivery often reports conflicting results. This study aimed to review the effectiveness of MgSO 4 on improving postoperative analgesia after CS systematically.

METHODS PubMed, Embase, and the Cochrane library were searched for randomized controlled trials (RCTs) published from inception to February 2020.

RESULTS A total of 880 women were included (440 in each group). MgSO 4 had a statistically significant effect compared to the control group on the highest VAS (weighted mean difference [WMD]B =B -0.74, 95% confidence interval [CI]= -1.03 to -0.46, pB
DISCUSSION MgSO 4 decreases the highest VAS in women who underwent general anesthesia, spinal anesthesia, or epidural for CS

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