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A longer duration of extended-release naltrexone (XR-NTX) treatment in individuals with opioid dependence was associated with improved outcomes and reduced rates of relapse in a study published in Addiction. Monthly visits for XR-NTX treatment of 395 patients with opioid dependence were retrospectively assessed. Patients were divided into subgroups according to the number of XR-NTX injections they received: 6 […]
Read MoreAuthors: Matthias Behrends, M.D. et al Anesthesiology 9 2018, Vol.129, 536-543. What We Already Know about This Topic: Hip arthroscopy is a surgical procedure growing in popularity The optimal approach to postoperative analgesia has not been identified What This Article Tells Us That Is New: The addition of preoperative fascia iliaca block using ropivacaine to the […]
Read MorePatients taking prescription opioids and gabapentin concomitantly have a 49% greater risk for opioid-related death than those treated with opioids only, according to a new Canadian study. A team of researchers led by Tara Gomes, PhD, MHSc, principal investigator of the Ontario Drug Policy Research Network (ODPRN), used administrative databases to compare opioid users who […]
Read MoreAuthors: Cassandra Wasson, DO, Alice Tsao, MD, Zheng Wang, MD Case Description A 45-year-old man presented to the emergency department (ED) as a trauma patient after a motor vehicle collision. He was a restrained passenger of a single-vehicle accident. The Glasgow Coma Scale (GCS) score was assessed as 9 in the field. The emergency medical services […]
Read MoreAuthors: Amie L. Severino, Ph.D. et al Anesthesiology 9 2018, Vol.129, 544-556. What We Already Know about This Topic: Pain resolves more quickly from cesarean delivery than other abdominal surgeries Pregnancy-related hormones such as oxytocin may reduce postoperative pain in women, although similar systems may function in men as well What This Article Tells Us That […]
Read MoreAuthors: Jonne Doorduin, Ph.D. et al Anesthesiology 9 2018, Vol.129, 490-501. What We Already Know about This Topic: Inspiratory muscle weakness delays weaning from mechanical ventilation, but the contributions of expiratory muscles activity are less well understood. What This Article Tells Us That Is New: Twenty adult patients receiving mechanical ventilation (more than 72 h) performed […]
Read MoreAuthors: Charles H. Brown, IV, M.D., M.H.S. et al Anesthesiology 9 2018, Vol.129, 406-416. What We Already Know about This Topic: Cardiac surgery is associated with cognitive decline and postoperative delirium The relationship between postoperative delirium and cognitive decline after cardiac surgery is unclear What This Article Tells Us That Is New: The development of postoperative […]
Read MoreAuthors: Dian-Shi Wang, M.D., Ph.D. et al Anesthesiology 9 2018, Vol.129, 477-489. What We Already Know about This Topic: Dexmedetomidine is effective in reducing delirium in the postoperative period and in the intensive care unit in patients and prevents memory deficits in experimental animals subjected to anesthesia. The mechanism by which dexmedetomidine preserves cognition is not […]
Read MoreAuthors: Alexander J. Butwick, M.B.B.S., F.R.C.A., M.S. et al Anesthesiology 9 2018, Vol.129, 448-458. What We Already Know about This Topic: Neuraxial labor analgesia for parturients is often recommended to avoid airway instrumentation in case of urgent surgical delivery The extent to which neuraxial use varies by maternal body mass index using modern, national data remains […]
Read MoreAuthors: Louise Y. Sun, M.D., S.M. et al Anesthesiology 9 2018, Vol.129, 440-447. What We Already Know about This Topic: Ischemic stroke after cardiac surgery is a devastating complication affecting approximately 2% of patients The relationship between hypotension occurring before, during, and after cardiopulmonary bypass and stroke remains unclear What This Article Tells Us That Is […]
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