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Authors: Lukas Pichler, M.D. et al Anesthesiology 10 2018, Vol.129, 689-699. What We Already Know about This Topic: The need for long-duration nonopioid pain relief after total knee arthroplasty has driven multimodal analgesic regimens, some of which include the administration of liposomal bupivacaine It is unclear whether the use of liposomal bupivacaine is reliably associated with […]
Read MoreAuthors: Samir Kendale, M.D. et al Anesthesiology 10 2018, Vol.129, 675-688. What We Already Know about This Topic: The ability to predict postinduction hypotension remains limited and challenging due to the multitude of data elements that may be considered Novel machine-learning algorithms may offer a systematic approach to predict postinduction hypotension, but are understudied What This […]
Read MoreAuthors: Christine K. Lee, M.S., Ph.D. et al Anesthesiology 10 2018, Vol.129, 649-662. What We Already Know about This Topic: Robust predictions are required to compare perioperative mortality among hospitals Deep neural network systems, a type of machine learning, can be used to develop highly nonlinear prediction models What This Article Tells Us That Is […]
Read MoreAuthors: Raphaël Cinotti, M.D., Ph.D. et al Anesthesiology published on September 18, 2018. What We Already Know about This Topic: The authors developed a score for predicting the risk of postoperative complications What This Article Tells Us That Is New: The score was developed from […]
Read MorePatients with V3 trigeminal neuralgia — particularly those with a large foramen ovale — may get greater benefit from bipolar vs unipolar radiofrequency thermocoagulation, according to research presented at the American Academy of Pain Medicine Annual Meeting, held in Vancouver, Canada. Trigeminal neuralgia is commonly treated with percutaneous radiofrequency thermocoagulation of the Gasserian ganglion. This is achieved […]
Read MoreExpected price increase 20 percent for all drugs after shortage versus 9 percent in absence of shortage Prices for drugs under shortage increase more than twice as quickly as expected in the absence of a shortage, according to a research letter published online Sept. 18 in the Annals of Internal Medicine. Inmaculada Hernandez, Pharm.D., Ph.D., from […]
Read MoreEUROPEAN LUNG FOUNDATION Paris, France: First results from a clinical trial of a procedure to open obstructed airways in patients with chronic obstructive pulmonary disease (COPD) have shown that it significantly reduces problems associated with the disease and is safe. Presenting findings from the AIRFLOW 2 phase II clinical trial, the principal investigator, Dr Dirk-Jan […]
Read MoreWritten by: David Ermak, DO Reviewed by: Sonia Vaida, MD A 31-year-old primigravida at 39 weeks’ gestation with no prenatal care presented to the labor and delivery unit in active labor. She had been diagnosed with multiple sclerosis (MS) at 28 years of age. She was treated with glatiramer acetate, but discontinued the medication due […]
Read MoreElizabeth A.M. Frost, MD Professor of Anesthesiology Mount Sinai Medical Center New York, New York Chiari Malformations What Are They? Chiari malformations (CMs) are structural defects in the base of the skull and cerebellum. The cerebellum, and especially the cerebellar tonsils, are situated above the foramen magnum. With CMs, however, these parts of the […]
Read MoreAuthors: delais G. Tsiotou et al Pediatric Anesthesia May 2018 Postanesthesia emergence delirium is a motor agitation state complicating pediatric anesthesia. We investigated the efficacy of dexmedetomidine in reducing emergence delirium in children undergoing tonsillectomy with and without adenoidectomy using total intravenous anesthesia with propofol. Methods This was a prospective, single‐center, double‐blind, randomized study. The primary […]
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