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Uncategorized Published - 7 November, 2018    By - Dr Clemens
Cognitive Effects of Perioperative Pregabalin: Secondary Exploratory Analysis of a Randomized Placebo-controlled Study

Authors: Marianne Myhre, M.D. et al  Anesthesiology October 17, 2018. What We Already Know about This Topic: Perioperative administration of pregabalin has been associated with decreased postoperative pain and opioid requirements What This Article Tells Us That Is New: This secondary analysis of data demonstrating that perioperative administration of pregabalin was associated with a reduction in […]

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Uncategorized Published - 7 November, 2018    By - Dr Clemens
Norepinephrine Infusion for Preventing Postspinal Anesthesia Hypotension during Cesarean Delivery: A Randomized Dose-finding Trial

Authors: Ahmed M. Hasanin, M.D., D.E.S.A. et al  Anesthesiology October 17, 2018. What We Already Know about This Topic: Hypotension after spinal anesthesia for cesarean delivery is common, usually treated with phenylephrine or ephedrine Norepinephrine was recently introduced in obstetric anesthesia but the optimal dose is unknown What This Article Tells Us That Is New: This […]

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Uncategorized Published - 7 November, 2018    By - Dr Clemens
Hospital laundering fails to kill diarrhea spores, study finds

By Allen Cone A study found hospital bedsheets cleaned in commercial washing machines with industrial detergent at high disinfecting temperatures failed to remove all traces of a bacteria that causes infectious diarrhea. Hospital bedsheets cleaned in commercial machines with industrial detergent at high disinfecting temperatures failed to remove all traces of a bacteria that causes […]

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Uncategorized Published - 6 November, 2018    By - Dr Clemens
Airway Management: The Less Popular Skill of Bag-mask Ventilation

Authors: Gerald P. Rosen, M.D. et al  Anesthesiology 11 2018, Vol.129, 1049-1050. To the Editor: As anesthesiologists, it is encouraging that recent attention has been paid to airway management improvements in and out of the operating suites. Our goals of positive patient safety outcomes have led to many recent airway management publications. The most recent of […]

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Uncategorized Published - 6 November, 2018    By - Dr Clemens
Propofol-based Total Intravenous Anesthesia Is Associated with Better Survival Than Desflurane Anesthesia in Colon Cancer Surgery

Authors: Zhi-Fu Wu, M.D. et al  Anesthesiology 11 2018, Vol.129, 932-941. What We Already Know about This Topic: Propofol may better preserve host defenses against cancer Whether cancer recurrence is less likely with propofol than volatile anesthesia remains unknown What This Article Tells Us That Is New: The authors conducted a propensity-matched retrospective analysis of 1,158 […]

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Uncategorized Published - 6 November, 2018    By - Dr Clemens
Effect of Equipotent Doses of Propofol versus Sevoflurane Anesthesia on Regulatory T Cells after Breast Cancer Surgery

Authors: Chung-Sik Oh, M.D., Ph.D. et al  Anesthesiology 11 2018, Vol.129, 921-931. What We Already Know about This Topic: Cluster of differentiation enzymes on regulatory T cells are immunosuppressive and promote cancer recurrence The investigators tested the hypothesis that cluster of differentiation 39 and 73 expression is increased less with propofol than sevoflurane What This Article […]

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Uncategorized Published - 6 November, 2018    By - Dr Clemens
Caffeine Accelerates Emergence from Isoflurane Anesthesia in Humans: A Randomized, Double-blind, Crossover Study

Authors: Robert Fong, M.D., Ph.D. et al  Anesthesiology 11 2018, Vol.129, 912-920. What We Already Know about This Topic: Caffeine may speed anesthetic emergence What This Article Tells Us That Is New: The authors tested the hypothesis that caffeine speeds anesthetic emergence Volunteers anesthetized with isoflurane were given caffeine (equivalent to 7.5 mg base) or placebo in […]

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Uncategorized Published - 6 November, 2018    By - Dr Clemens
Differences of Recovery from Rocuronium-induced Deep Paralysis in Response to Small Doses of Sugammadex between Elderly and Nonelderly Patients

Authors: Takahiro Muramatsu, M.D. et al  Anesthesiology 11 2018, Vol.129, 901-911. What We Already Know about This Topic: Sugammadex may be the best available drug to reverse residual neuromuscular blockade produced by rocuronium and vecuronium A 5% incidence of residual neuromuscular blockade has been reported after administering sugammadex without neuromuscular monitoring Elderly patients have been reported […]

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Uncategorized Published - 5 November, 2018    By - Dr Clemens
Evaluate risk and strategize to reduce the need for reintubation

Intubation is a standard part of airway management in the O.R., ICU and other settings. At some point, every intubation will be followed by an extubation. But what if the extubation has complications? Few anesthesiologists think about strategies for reintubation until problems have already begun to escalate. “Extubation has percolated into most airway guidelines at […]

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Uncategorized Published - 5 November, 2018    By - Dr Clemens
Comparison of the TOFscan and the TOF-Watch SX during Recovery of Neuromuscular Function

Authors: Glenn S. Murphy, M.D. et al  Anesthesiology 11 2018, Vol.129, 880-888. What We Already Know about This Topic: Monitoring of neuromuscular function recovery using quantitative methods improves patient outcome However, the application of quantitative monitoring is infrequent, in part because current devices are complex and application is time consuming What This Article Tells Us That […]

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