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Authors: Wilson, Jenna et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005649 This prospective randomized controlled trial evaluated whether intraoperative ketamine reduces acute postsurgical pain in women undergoing breast cancer surgery, while also examining whether baseline temporal summation of pain (a measure of central sensitization) influences ketamine’s efficacy. A total of 225 patients were randomized to […]
Read MoreAuthors: Zhu, Youzhuang et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005800 This randomized controlled trial evaluated whether S-ketamine can reduce postoperative delirium (POD) in elderly patients undergoing total hip or knee arthroplasty under neuraxial anesthesia. The study enrolled 372 patients between November 2023 and October 2024 at a high-volume arthroplasty center with standardized perioperative care […]
Read MoreAuthors: Shen, Fangming et al. Anesthesiology 2025 Oct 14 | DOI: 10.1097/ALN.0000000000005707 This multicenter randomized clinical trial (the AmPRAEC study) evaluated how different anesthesia-maintenance strategies affect postoperative respiratory adverse events (PRAEs) in children undergoing adenotonsillectomy. The investigators enrolled 760 children aged 0–12 years at 12 hospitals in China and randomly allocated them to one of […]
Read MoreHardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]
Read MoreAuthors: Jiang, Xue et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005731 This large longitudinal cohort study investigated whether chronic widespread pain (CWP) contributes to cognitive decline and dementia, as well as potential underlying mechanisms involving brain structure and systemic inflammation. Using data from nearly 190,000 UK Biobank participants followed over 13 years, researchers examined self-reported […]
Read MoreAuthors: Calabrese, Alberto et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005633 This comprehensive narrative review examines the expanding role of renin–angiotensin system (RAS) modulation in critical care, focusing on both classical and alternative pathways. The authors explore how the dual RAS axes—one promoting vasoconstriction and inflammation, the other vasodilation and tissue protection—may be therapeutically targeted […]
Read MoreAuthor: Xue, Fu-Shan M.D. et al Anesthesiology October 21, 2025. | DOI: 10.1097/ALN.0000000000005703 This Letter to the Editor comments on Zhang et al.’s recent study evaluating pyridoxine as part of a multimodal strategy for preventing postoperative nausea and vomiting (PONV) following gynecologic laparoscopic surgery. The authors commend the findings but raise concerns about potential confounding factors and the […]
Read MoreAuthors: Hight, Darren et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005762 This letter to the editor exposes a long-standing technical flaw in Bispectral Index (BIS) monitors (Medtronic, Ireland) that directly affects calculation of the spectral edge frequency 95 (SEF95), a standard electroencephalographic (EEG) measure used to gauge anesthetic depth. The authors—building on prior reports of […]
Read MoreHardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]
Read MoreAuthor: Francesca Mathewes Becker’s ASC Review ASC leaders face a near impossible situation as anesthesia reimbursement rates stagnate and decline, all while other pressures, including staffing issues and operational costs weigh on profitability. Two leaders recently joined Becker’s to discuss their strategies for surviving the anesthesia cost squeeze. Editor’s note: Responses have been lightly edited for clarity and length. Question: What […]
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