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Pharmaceutical costs are already a large share of most health organizations’ budgets and this year’s inflation rate may increase drug budgets. Author: Jeff Lagasse Health systems, including inpatient and non-acute environments, can expect a 4.57% increase in pharmaceutical spend for 2020. Vizient, which revealed that finding in its recent 2019 Drug Price Forecast, predicts a […]
Read MoreBy Kelly Young Roughly half of opioid-naive inpatients are given an opioid during their hospital stay, finds a study of one U.S. health network in the Annals of Internal Medicine. Researchers examined opioid prescribing for nearly 150,000 opioid-naive inpatients in a network of Pennsylvania hospitals between 2010 and 2014. Of the 48% who received an opioid […]
Read MoreAUTHORS: Sun R et al BMJ Open 9 (4), e025850 (Apr 2019) INTRODUCTION: Delirium is very common in patients admitted to intensive care unit (ICU), and may worsen survival in these patients. Several meta-analyses have evaluated the antidelirium effects of dexmedetomidine in ICU patients, but their findings were inconsistent. Recently, several large multicentre randomised clinical […]
Read MoreAUTHORS: Matchett, Gerald MD et al Anesthesia & Analgesia: May 2019 BACKGROUND: Endotracheal tubes (ETTs) are commonly secured with tape to prevent undesirable tube migration. Many methods of taping have been described, although little has been published comparing various methods of taping to one another. In this study, we evaluated several methods for securing ETTs with tape. […]
Read MoreAUTHORS: Chiumello, Davide MD et al Anesthesia & Analgesia: May 2019 BACKGROUND: During thoracic surgery, patients are usually positioned in lateral decubitus and only the dependent lung ventilated. The ventilated lung is thus exposed to the weight of the contralateral hemithorax and restriction of the dependent chest wall. We hypothesized that mechanical power would increase during one-lung […]
Read MoreAUTHORS: Weil, Gregoire MD et al Anesthesia & Analgesia: May 2019 BACKGROUND: The end-expiratory occlusion test predicts fluid responsiveness in ventilated intensive care patients; however, its utility in the operating room is questioned. We assessed end-expiratory occlusion test in laparotomic surgery for predicting volume expansion. METHODS: Forty-six patients were included in this study: stage 1 (n = 26) […]
Read MoreAUTHORS: Gaver, Renee S. MD et al Anesthesia & Analgesia: May 2019 BACKGROUND: Sugammadex, with its novel mechanism of action of encapsulation and noncompetitive binding of aminosteroid neuromuscular-blocking agents (rocuronium and vecuronium), may offer distinct advantage to pediatric patients where residual neuromuscular blockade may be poorly tolerated. Data describing its use in the pediatric population are limited, […]
Read MoreAuthors: Rhee, Chanu MD, MPH et al Critical Care Medicine: September 2019 – Volume 47 – Issue 9 – p 1169-1176 Objectives: Prior studies have reported that hospital-onset sepsis is associated with higher mortality rates than community-onset sepsis. Most studies, however, have used inconsistent case-finding methods and applied limited risk-adjustment for potential confounders. We used consistent sepsis criteria and detailed electronic clinical data […]
Read MoreBy Kelly Young Rates of drug overdose deaths in cities have overtaken those in rural areas, according to new data from the CDC’s National Center for Health Statistics. From 2007 through 2015, rural areas led urban areas in overdose deaths. But then in 2016 and 2017, the age-adjusted drug rate of drug overdose deaths was […]
Read MoreAUTHORS: Yang M et al BMJ Open 9 (4), e025091 (Apr 2019) OBJECTIVES: Inadequate postoperative pain control is common and is associated with poor clinical outcomes. This study aimed to identify preoperative predictors of poor postoperative pain control in adults undergoing inpatient surgery. RESULTS: Thirty-three studies representing 53 362 patients were included in this review. Significant […]
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