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Uncategorized Published - 11 September, 2019    By - Dr Clemens
Induction opioids for caesarean section under general anaesthesia: a systematic review and meta-analysis of randomised controlled trials

Authors: L.D. White et al International Journal of Obstetric Anesthesia Highlights •Opioids are effective agents to suppress the pressor response to laryngoscopy. •Remifentanil and alfentanil did not impact Apgar scores. •Remifentanil and alfentanil did not impact neonatal respiratory support requirement. Introduction The adverse effects of induction opioids on the neonate are poorly characterised. The study […]

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Uncategorized Published - 11 September, 2019    By - Dr Clemens
Intra-op Methadone Prompts Lower Post-op Pain Scores Than Other Opioids

Author: Michael Vlessides Anesthesiology News Has the time come for intraoperative methadone to be considered a legitimate postoperative analgesic? A study of the often beleaguered agent’s safety and efficacy indicates the answer may well be yes. The meta-analysis—by Thomas Cheriyan, MD, and his colleagues at Augusta University, in Georgia—concluded that use of intraoperative methadone resulted […]

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Uncategorized Published - 11 September, 2019    By - Dr Clemens
SHEA Issues Infection Control Guidance for OR Anesthesia Care

Author: Thomas Rosenthal Anesthesiology News The Society for Healthcare Epidemiology of America (SHEA) released new expert guidance to improve infection control practices specific to OR anesthesia care that aims to help protect patients from nosocomial infections (Infect Control Hosp Epidemiol 2019:1-17). The new SHEA expert guidance is needed because “infection prevention and control policies specific to […]

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Uncategorized Published - 11 September, 2019    By - Dr Clemens
Population Pharmacokinetics of Intraperitoneal Bupivacaine Using Manual Bolus Atomization Versus Micropump Nebulization and Morphine Requirements in Young Children

AUTHORS: Meier, Petra M. MD et al Anesthesia & Analgesia: May 20, 2019 BACKGROUND: Intraperitoneal (IP) administration of local anesthetics is used in adults and children for postoperative analgesia after laparoscopic surgery. Population pharmacokinetics (PK) of IP bupivacaine has not been determined in children. Objectives of this study were (1) to develop a population PK model […]

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Uncategorized Published - 11 September, 2019    By - Dr Clemens
The Long-Term Health Effects of September 11, 2001

Author: Natasha Persaud Renal and Urology News Thousands of responders, workers, and volunteers participated in the rescue and cleanup efforts at the World Trade Center (WTC), the Pentagon, and the crash site near Shanksville, Pennsylvania during September 11, 2001 and ensuing months. Many workers and residents were exposed to an untold mix of asbestos, alkaline […]

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Uncategorized Published - 11 September, 2019    By - Dr Clemens
Haloperidol, Ziprasidone Ineffective For Delirium in Critical Illness

This is for our readers who also take care of ICU patients. AUTHOR: Bob Kronemyer Anesthesiology News Two antipsychotic medications that are often used to treat delirium in the ICU, namely haloperidol and ziprasidone, do not significantly alter the duration of the disturbance, according to a study in The New England Journal of Medicine (2018;379:2506-2516). “After 40 […]

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Uncategorized Published - 10 September, 2019    By - Dr Clemens
Effect of Sugammadex on Postoperative Myasthenic Crisis in Myasthenia Gravis Patients

AUTHORS: Mouri, Hideyuki MD et al Anesthesia & Analgesia: May 20, 2019 BACKGROUND: In myasthenia gravis (MG) patients, postoperative myasthenic crisis, and residual neuromuscular blocking agent (NMBA) can cause respiratory failure that requires mechanical ventilation. However, it remains unclear whether the use of sugammadex for NMBA reversal reduces postoperative myasthenic crisis in MG patients undergoing surgery. We […]

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Uncategorized Published - 10 September, 2019    By - Dr Clemens
Monitoring Identifies Those at High Risk for Opioid-Induced Respiratory Depression

AUTHOR: Thomas Rosenthal Anesthesiology News A new monitoring tool helps predict those patients on a general care floor who are at high risk for developing opioid-induced respiratory depression (OIRD). Ashish Khanna, MD, FCCP, FCCM, an anesthesiologist, intensivist and associate professor of anesthesiology at Wake Forest School of Medicine, in Winston-Salem, N.C., presented preliminary results from […]

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Uncategorized Published - 10 September, 2019    By - Dr Clemens
Ketamine Reduces Opioid Need in Severely Injured Patients

AUTHOR: Chase Doyle Anesthesiology News Used as a Safe Adjunct for Rib Fracture The first randomized, double-blind, placebo-controlled trial of ketamine in patients with rib fractures has shown that low-dose ketamine infusions are a safe adjunct in the setting of treatment of acute traumatic pain, with no significant differences in side effects noted between the […]

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Uncategorized Published - 10 September, 2019    By - Dr Clemens
Prevalence of Isoelectric Electroencephalography Events in Infants and Young Children Undergoing General Anesthesia

AUTHORS: Yuan, Ian MD et al Anesthesia & Analgesia: May 15, 2019 BACKGROUND: In infants and young children, anesthetic dosing is based on population pharmacokinetics and patient hemodynamics not on patient-specific brain activity. Electroencephalography (EEG) provides insight into brain activity during anesthesia. The primary goal of this prospective observational pilot study was to assess the prevalence of […]

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