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Uncategorized Published - 8 October, 2019    By - Dr Clemens
Combined Neuraxial and General Anesthesia Significantly Improves Perioperative Outcomes Following Elective Open Abdominal Aortic Aneurysm Repair

Authors: Konrad Salata, MD et al Journal of Vascular Surgery October 2019 Volume 70, Issue 4, Page e110 Objective Evidence for the use of neuraxial anesthesia (NA) in the context of open abdominal aortic aneurysm (AAA) repair is sparse. The purpose of this study was to determine the 90-day outcomes of combined general and NA […]

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Uncategorized Published - 8 October, 2019    By - Dr Clemens
Adverse side effects and route of administration of opioids in combined spinal-epidural analgesia for labour

Authors: L. Grangier et al International Journal of Obstetric Anesthesia Highlights Meta-analysis of side effects after combined spinal epidural analgesia (CSE) in labour. Compared with epidural analgesia, side effects are increased. Administration of opioid, added to local anaesthetic, is a likely cause. Bradycardia occurs more often, regardless of the route of opioid administration. Hypotension occurs […]

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Uncategorized Published - 8 October, 2019    By - Dr Clemens
Association Between Post–Dural Puncture Headache After Neuraxial Anesthesia in Childbirth and Intracranial Subdural Hematoma

Authors: lbert R. Moore, MD et al JAMA Neurol. September 16, 2019. Key Points Question  Do postpartum women with post–dural puncture headache secondary to neuraxial anesthesia have an increased risk of intracranial subdural hematoma? Findings  In this cohort study of 22 130 815 deliveries, there was a post–dural puncture headache rate of 309 per 100 000 deliveries and a subdural […]

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Uncategorized Published - 8 October, 2019    By - Dr Clemens
Prospective Association of Serum Opioid Levels and Clinical Outcomes in Patients With Cancer Pain Treated With Intrathecal Opioid Therapy

AUTHORS: Brogan, Shane E. MB BCh et al Anesthesia & Analgesia: June 12, 2019 BACKGROUND: Opioids remain the mainstay of cancer pain management but are associated with systemic toxicity. In refractory cancer pain, intrathecal therapy (ITT) is associated with improved pain control, reduced systemic side effects, and improved survival. It has been assumed that ITT decreases systemic […]

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Uncategorized Published - 8 October, 2019    By - Dr Clemens
Sleep apnea, resistant hypertension pose highest risk for heart attack

Author: Tauren Dyson UPI People with severe forms of sleep apnea also often have very high blood pressure, which new research suggests carries risk for heart health events. Patients with resistant high blood pressure, which can require at least three drugs to control, have the highest risk of suffering a heart attack or cardiac episode, […]

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Uncategorized Published - 7 October, 2019    By - Dr Clemens
Prevention of hypotension after spinal anaesthesia for caesarean section: a systematic review and network meta‐analysis of randomised controlled trials

Authors: J. P. Fitzgerald et al Anesthesia September 2019 Summary Spinal anaesthesia for caesarean section commonly causes maternal hypotension. This systematic review and network meta‐analysis compared methods to prevent hypotension in women receiving spinal anaesthesia for caesarean section. We selected randomised controlled trials that compared an intervention to prevent hypotension with another intervention or inactive […]

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Uncategorized Published - 7 October, 2019    By - Dr Clemens
TEE Measurements Can Underestimate Severity of Aortic Stenosis

Author: Michael Vlessides Anesthesiology News Transesophageal echocardiography (TEE) measurements made during general endotracheal anesthesia with mechanical ventilation underestimate the severity of aortic stenosis in patients undergoing cardiac surgery, according to a new study. Pressure gradients in these situations also were significantly greater during the inspiratory phase than the expiratory phase. Given these findings, the investigators […]

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Uncategorized Published - 7 October, 2019    By - Dr Clemens
Patients Receiving Ketamine Plus Dexmedetomidine Combo Need Monitoring

Author: Thomas Rosenthal Anesthesiology News Surgical patients who receive analgesic doses of ketamine together with dexmedetomidine should be closely monitored before and immediately after they leave the hospital because of the potential neurocognitive and behavioral effects of the drug combination, a study has found. “At analgesic doses required for pain relief, ketamine administered in combination […]

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Uncategorized Published - 7 October, 2019    By - Dr Clemens
Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy

Authors: Silvia Schönenberger, MD et al JAMA. 2019;322(13):1283-1293. doi:10.1001/jama.2019.11455 Question  Is there a difference in functional outcome at 3 months between patients who receive general anesthesia or procedural sedation during stroke thrombectomy? Findings  In this individual patient data meta-analysis of 3 randomized clinical trials that included 368 patients with acute ischemic stroke in the anterior circulation, the use […]

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Uncategorized Published - 7 October, 2019    By - Dr Clemens
Treatment for chronic neuropathic pain gets to the brain via a novel route, without surgery

Author: Ellen Goldbaum University at Buffalo University at Buffalo researchers who previously discovered how chronic neuropathic pain arises in the brain have now developed a treatment to block it. The research conducted by scientists in the Jacobs School of Medicine and Biomedical Sciences at UB was published online July 31 in the journal Brain, Behavior, and […]

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