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Authors: Huafeng Wei, M.D.,Ph.D. et al Anesthesiology 2019 We compared the effects and mechanisms of sevoflurane vs. propofol at equipotent dose (1 MAC vs 2 µM) on cell survival, proliferation and migration, intracellular calcium homeostasis in different types of human breast normal or cancer cells. Methods We used estrogen receptor positive (MCF7) and estrogen receptor […]
Read MoreCommon antidepressants interact with tramadol to make it less effective for pain relief, according to a study published in Pharmacotherapy. The findings have important implications for the opioid epidemic, suggesting that some patients suspected of drug-seeking may in fact be under-medicated and just are seeking more effective pain relief. The results of the study could also […]
Read MoreThe Food and Drug Administration is recommending manufacturers put a warning label on their breast implant devices so women are more aware of the risks of serious complications. The big picture: Thousands of women who received implants have reported severe muscle and joint pain, weakness, cognitive difficulties and fatigue, the New York Times reports. This and a few recalls […]
Read MoreAuthors: E. Keogh et al European Journal of Pain Oct 29, 2019 Background Gender beliefs help explain the variation found in pain amongst men and women. Gender norms and expectations are thought to affect how men and women report and express pain. However, less is known about how such beliefs are related to pain outside […]
Read MoreAUTHORS: Reynolds, J. Wells MD et al Anesthesia & Analgesia: August 2019 – Volume 129 – Issue 2 – p 536-542 BACKGROUND: Axillary pain is common after arthroscopic shoulder surgery with an open subpectoral biceps tenodesis. We hypothesized that adding a pectoral nerve block II (Pecs II) to an interscalene block (ISB) would improve postoperative analgesia […]
Read MoreAuthors: Chunyuan Qiu, M.D., M.Sc. et al Anesthesiology 2019 Introduction: Enhanced recovery after surgery (ERAS) has enjoyed tremendous success in changing surgical outcomes .1 However, the value for same day surgery has not been well studied, partially due to the difficulty in actuating additional safety, quality, and cost in the ambulatory setting. By using the ERAS principles, […]
Read MoreAuthors: Shadi Gadalla, M.B.,Ch.B.et al Anesthesiology 2019 INTRODUCTION: Patients undergoing colorectal surgery may experience high rates of complications. In addition to superior analgesia, the purported benefits of perioperative thoracic epidural analgesia (TEA) include the reduction in the incidence of pulmonary morbidity, namely pneumonia and myocardial events. Historical series have estimated upwards of 10% of patients […]
Read MorePatients who receive a post-surgery prescription of ibuprofen with a rescue prescription of acetaminophen/oxycodone use less opioids than those only prescribed acetaminophen/oxycodone, according to a study presented at the 2019 American Orthopaedic Society for Sports Medicine Annual Meeting. “The current opioid epidemic demands [that] physicians seek ways to decrease patients’ requirements of narcotic medications without […]
Read MoreAUTHORS: Kim, David H. MD et al Anesthesia & Analgesia: August 2019 – Volume 129 – Issue 2 – p 526-535 BACKGROUND: Periarticular injections (PAIs) are becoming a staple component of multimodal joint pathways. Motor-sparing peripheral nerve blocks, such as the infiltration between the popliteal artery and capsule of the posterior knee (IPACK) and the adductor […]
Read MoreAUTHORS: Nomura, Yohei MD et al Anesthesia & Analgesia: August 2019 – Volume 129 – Issue 2 – p 507-514 BACKGROUND: Frailty is a geriatric syndrome thought to identify the most vulnerable older adults, and morbidity and mortality has been reported to be higher for frail patients after cardiac surgery compared to nonfrail patients. However, the […]
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