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Uncategorized Published - 9 December, 2019    By - Dr Clemens
Population Pharmacokinetics of Periarticular Ketorolac in Adult Patients Undergoing Total Hip or Total Knee Replacement Surgery

AUTHORS: Gurunathan, Usha FANZCA et al Anesthesia & Analgesia: September 2019 – Volume 129 – Issue 3 – p 701-708 BACKGROUND: Ketorolac tromethamine has been used for joint infiltration by the orthopedic surgeons as a part of postoperative multimodal analgesia. The objective of this study is to investigate the pharmacokinetic properties of S (−) and R […]

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Uncategorized Published - 9 December, 2019    By - Dr Clemens
Babies Born by C-Section Have Different Gut Microbes Than Vaginally Delivered Infants

I thought this was interesting so I wanted to share with our readers. Method of delivery can influence the bacteria in infants’ guts, according to a new study, but differences were found to disappear within nine months Author: Sarah Elizabeth Richards For the past decade, scientists have been fascinated by how the bacteria in our […]

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Uncategorized Published - 6 December, 2019    By - Dr Clemens
Airway Management in Patients With Oropharyngeal Masses

Authors: Avery Tung, MD, FCCM et al Anesthesiology News Not Only Successful Intubations but Avoidance of Complications Choosing an airway management technique based primarily on success rate is itself a form of outcome bias that may lead to inadequate planning or preparation. Introduction Airway management in patients with oropharyngeal (OP) masses may be extremely challenging.1,2 Depending […]

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Uncategorized Published - 6 December, 2019    By - Dr Clemens
Intraoperative Ketamine in Total Knee Arthroplasty Does Not Decrease Pain and Narcotic Consumption

AUTHORS: Tan T et al Journal of Arthroplasty 34 (8), 1640-1645 (Aug 2019) BACKGROUND Multiple studies have demonstrated that ketamine, a glutamate receptor blocker, may decrease postoperative pain in abdominal and orthopedic surgeries. However, its role with spinal anesthesia and total knee arthroplasty (TKA) remains unknown. The purpose of this study is to determine the […]

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Uncategorized Published - 6 December, 2019    By - Dr Clemens
Effectiveness of Magnesium in Preventing Shivering in Surgical Patients

AUTHORS: Kawakami, Hiromasa MD et al Anesthesia & Analgesia: September 2019 – Volume 129 – Issue 3 – p 689-700 BACKGROUND: Clinical trials regarding the antishivering effect of perioperative magnesium have produced inconsistent results. We conducted a systematic review and meta-analysis with Trial Sequential Analysis to evaluate the effect of perioperative magnesium on prevention of shivering. […]

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Uncategorized Published - 6 December, 2019    By - Dr Clemens
Cuff Leaks in the ICU: Etiologies, Management and Complications

Anesthesiology News Authors: Sagar Patel, DO et al Anesthesia providers are often confronted with the management of a “cuff leak” in mechanically ventilated patients in the OR and ICU.1 Certainly, the advantage of the OR environment is that the patient is in a relatively more controlled setting, monitored by health care providers (HCPs) who are familiar […]

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Uncategorized Published - 6 December, 2019    By - Dr Clemens
Nearly All Types of Menopausal Hormone Therapy Tied to Higher Breast Cancer Risk

Author: Amy Orciari Herman Edited by William E. Chavey, MD, MS All types of menopausal hormone therapy (HT), except vaginal estrogen, are associated with increased breast cancer risk, according to a large meta-analysis in the Lancet. Researchers examined prospective data on over 100,000 postmenopausal women who developed breast cancer. Among the other findings: Excess risk for breast […]

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Uncategorized Published - 5 December, 2019    By - Dr Clemens
Invasive Respiratory or Vasopressor Support and/or Death as a Proposed Composite Outcome Measure for Perioperative Care Research

AUTHORS: Mizota, Toshiyuki MD, PhD et al Anesthesia & Analgesia: September 2019 – Volume 129 – Issue 3 – p 679-685 BACKGROUND: There is a need for a clinically relevant and feasible outcome measure to facilitate clinical studies in perioperative care medicine. This large-scale retrospective cohort study proposed a novel composite outcome measure comprising invasive respiratory […]

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Uncategorized Published - 5 December, 2019    By - Dr Clemens
Transport of Critically Ill Patients by the Anesthesia Versus the Intensive Care Unit Service: A Before–After Study of Operating Room Workflows

AUTHORS: Dupont, Frank W. MD et al Anesthesia & Analgesia: September 2019 – Volume 129 – Issue 3 – p 671-678 BACKGROUND: We implemented a new policy at our institution where the responsibility for intensive care unit (ICU) patient transports to the operating room (OR) was changed from the anesthesia to the ICU service. We hypothesized […]

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Uncategorized Published - 5 December, 2019    By - Dr Clemens
Coagulation Factor Levels and Underlying Thrombin Generation Patterns in Adult Extracorporeal Membrane Oxygenation Patients

AUTHORS: Mazzeffi, Michael MD, MPH, MSc et al Anesthesia & Analgesia: September 2019 – Volume 129 – Issue 3 – p 659-666 BACKGROUND: There is a paucity of data on the underlying procoagulant–anticoagulant balance during extracorporeal membrane oxygenation (ECMO). We hypothesized that adult ECMO patients would have an imbalance between procoagulant and anticoagulant factors, leading to […]

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