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Authors: Mohamed F. Mostafa et al European Journal of Pain January 2020 Volume 24 Issue 1 pages 182-191 Background Various adjuvants were added to intrathecal anaesthetics to improve quality of the block and postoperative analgesia. We hypothesized that intrathecal dexmedetomidine and magnesium sulphate (MgSO4) may add similar effects. Our objectives were to compare their effects […]
Read MoreAuthors: Moriyoshi Oji et al BMC Anesthesiology volume 19, Article number: 169 (2019) Background We previously demonstrated that lubrication of an endotracheal tube (ETT) cuff with K-Y™ jelly strongly and significantly inhibited the increase in cuff pressure during nitrous oxide (N2O) exposure in vitro. However, in our previous study, we identified critical differences between some influential factors, such as the […]
Read MoreAuthors: Ferrari MD et al. Lancet 2019 Aug 16 Tessitore A and Russo A. Lancet 2019 Aug 16 Fremanezumab is a well-tolerated and effective preventive therapy in patients with migraine for whom two to four preventives have failed. Researchers conducted a phase IIIb randomized controlled trial with fremanezumab, a calcitonin gene-related peptide (CGRP) monoclonal antibody, funded by the […]
Read MoreAuthors: Frederik Vilhelmsen et al BMC Anesthesiology volume 19, Article number: 165 (2019) Background Nerve block of the lateral femoral cutaneous nerve (LFCN) is a predominantly sensory block. It reduces pain following total hip arthroplasty (THA), but the non-responder rate is high. We hypothesized, that an increased volume of ropivacaine, would result in greater coverage of incisions used for THA. […]
Read MoreMariana R. S. Ceschim, MD and Keith A. Candiotti, MD Anesthesiology News In contradiction to the advances in medicine in recent decades, infectious diseases are on the rise.1 Environmental changes due to population shifts, climate change and microbial adaptations have prompted the spread of emerging and reemerging infections.1,2 These diseases can present with airway complications, respiratory and […]
Read MoreAUTHORS: Naylor, Amanda J. MA et al Anesthesia & Analgesia: September 2019 BACKGROUND: Continuous blood pressure monitoring may facilitate early detection and prompt treatment of hypotension. We tested the hypothesis that area under the curve (AUC) mean arterial pressure (MAP) <65 mm Hg is reduced by continuous invasive arterial pressure monitoring. METHODS: Adults having noncardiac surgery were randomly […]
Read MoreAUTHORS: Sabourdin, Nada MD et al Anesthesia & Analgesia: September 2019 BACKGROUND: Pupillometry monitoring under general anesthesia is based on the assumption that pupillary diameter variations reflect the adequacy of the provided analgesia to the intensity of the nociceptive surgical stimulus. The accurate interpretation of pupillometric data requires establishing clearly what the expected baseline unstimulated pupillary diameter […]
Read MoreAuthor: Michael Vlessides Anesthesiology News Ultrasound-guided rectus sheath block proves superior to field block with respect to perioperative pain control and stress response in patients undergoing midline hernia repair, new research has concluded. The team of Egyptian investigators behind the trial stressed that ultrasound guidance reduces the risk for accidental bowel puncture when performing the […]
Read MoreNonsteroidal anti-inflammatory drugs (NSAIDs) can help to control the pain and inflammation in patients with osteoarthritis (OA), but the drugs may contribute to cardiovascular side effects in these individuals, according to a study published in Arthritis & Rheumatology. The study matched 7,743 patients with OA with 23,229 controls without OA. The risk of developing cardiovascular disease […]
Read MoreAUTHORS: Takeshita, Shusuke MD et al Anesthesia & Analgesia: September 2019 BACKGROUND: Incomplete reversal with a recommended 5-g dose of idarucizumab has been reported in patients with excessively high dabigatran concentrations. A timely detection of reversal failure after idarucizumab using whole blood (WB) coagulation testing is clinically useful. The aims of this study were to determine residual […]
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