Uncategorized

Uncategorized Published - 11 May, 2020    By - Dr Clemens
OSA, OIRD and Airway Obstruction: Vigilance Required

Authors:  Davide Cattano, MD, PhD, FASA et al Anesthesiology News Opioid-induced respiratory depression (OIRD) has been recognized as one of the most dramatic and serious complications from the perioperative use of opioid analgesics. Current international efforts to publicize to the lay public the potential effects of misusing opioids, such as the risk for addiction, have […]

Read More
Uncategorized Published - 11 May, 2020    By - Dr Clemens
Association Between Perioperative Hypotension and Delirium in Postoperative Critically Ill Patients

AUTHORS: Maheshwari, Kamal MD et al  Anesthesia & Analgesia: March 2020 – Volume 130 – Issue 3 – p 636-643 BACKGROUND: Postoperative delirium is common in critically ill patients, with a reported incidence of 11%–43%, and is associated with significant morbidity and cost. Perioperative hypotension and consequent brain hypoperfusion may contribute. We, therefore, tested the […]

Read More
Uncategorized Published - 11 May, 2020    By - Dr Clemens
Remdesivir Trials Suggest Potential Benefit in COVID-19; FDA Expected to Authorize the Drug

By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Findings from several trials of remdesivir for novel coronavirus disease (COVID-19) were announced on Wednesday. The National Institutes of Health reported preliminary findings from a randomized, placebo-controlled trial of intravenous remdesivir in nearly 1100 patients hospitalized with COVID-19 with lung involvement, […]

Read More
Uncategorized Published - 11 May, 2020    By - Dr Clemens
Do ACEIs/ARBs Affect Severity, Mortality Risk in Hospitalized COVID-19 Patients with Hypertension?

Author: Kaitlyn D’Onofrio docwirenews The effects of COVID-19 range from presenting no symptoms at all to death. As experts try to determine what patient factors may affect disease severity and mortality risk from patient to patient, a new study assessed the association between angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) and severity of […]

Read More
Uncategorized Published - 8 May, 2020    By - Dr Clemens
Ultrasound-Assisted Versus Landmark-Guided Spinal Anesthesia in Patients With Abnormal Spinal Anatomy

AUTHORS: Park, Sun-Kyung MD et al Anesthesia & Analgesia: March 2020 – Volume 130 – Issue 3 – p 787-795 BACKGROUND:  Spinal anesthesia using a surface landmark–guided technique can be challenging in patients with anatomical alterations of the lumbar spine; however, it is unclear whether using ultrasonography can decrease the technical difficulties in these populations. […]

Read More
Uncategorized Published - 8 May, 2020    By - Dr Clemens
Practical Training of Anesthesia Clinicians in Electroencephalogram-Based Determination of Hypnotic Depth of General Anesthesia

AUTHORS: Bombardieri, Anna Maria MD, PhD et al Anesthesia & Analgesia: March 2020 – Volume 130 – Issue 3 – p 777-786 BACKGROUND:  Electroencephalographic (EEG) brain monitoring during general anesthesia provides information on hypnotic depth. We hypothesized that anesthesia clinicians could be trained rapidly to recognize typical EEG waveforms occurring with volatile-based general anesthesia. METHODS: […]

Read More
Uncategorized Published - 8 May, 2020    By - Dr Clemens
Ultrasound-assisted molecule delivery looks to preserve blood for years

Source: American Institute of Physics. “Ultrasound-assisted molecule delivery looks to preserve blood for years.” Science Daily 21 April 2020. Summary: Blood can typically be stored for only six weeks after donation, but a potential solution attempts to dry blood by using a sugar-based preservative. New work in ultrasound technology looks to provide a path to […]

Read More
Uncategorized Published - 8 May, 2020    By - Dr Clemens
Assessment of Fluid Responsiveness in Prone Neurosurgical Patients Undergoing Protective Ventilation: Role of Dynamic Indices, Tidal Volume Challenge, and End-Expiratory Occlusion Test

AUTHORS: Messina, Antonio MD, PhD et al Anesthesia & Analgesia: March 2020 – Volume 130 – Issue 3 – p 752-761 BACKGROUND:  In patients in the prone position, the reliability of pulse pressure variation and stroke volume variation (PPV and SVV) and the use of functional hemodynamic tests to predict fluid responsiveness have not previously […]

Read More
Uncategorized Published - 8 May, 2020    By - Dr Clemens
Fibrinogen Concentrate as an Alternative to Cryoprecipitate in a Postcardiopulmonary Transfusion Algorithm in Infants Undergoing Cardiac Surgery

AUTHORS: Downey, Laura A. MD et al Anesthesia & Analgesia: March 2020 – Volume 130 – Issue 3 – p 740-751 BACKGROUND:  Infants undergoing cardiac surgery are at risk for bleeding and massive transfusion due to an immature coagulation system, complex surgeries, and cardiopulmonary bypass (CPB) effects. Hemodilution from CPB promotes an acquired hypofibrinogenemia that […]

Read More
Uncategorized Published - 8 May, 2020    By - Dr Clemens
Improving Smoking Cessation Outcomes Through Tailored-Risk Patient Messages at a University Hospital Tobacco Cessation Service

Authors: David Gonzales, PhD The Joint Commission VOLUME 46, ISSUE 5, P 250-260, MAY 01, 2020 Background Postdischarge follow-up is a critical step for increasing effectiveness of hospital smoking cessation treatment. A quality improvement project was undertaken at an academic medical center tobacco cessation consult service to evaluate whether a tailored message (TM) linking immediate […]

Read More