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Author: Michael Walter Cardiovascular Business Neuroscientists have developed a new protein, TAT-DP-2, that could limit stroke-related brain damage, sharing their findings in Science Advances. The protein was designed to prevent cell death through the disruption of two specific Kv2.1 channels. This keeps potassium from leaving the cells in question, which completely changes how they react during […]
Read MoreAUTHORS: Sylvie D. Aucoin, M.D., M.Sc., F.R.C.P.C. et al Anesthesiology 7 2020, Vol.133, 78-95. Background: A barrier to routine preoperative frailty assessment is the large number of frailty instruments described. Previous systematic reviews estimate the association of frailty with outcomes, but none have evaluated outcomes at the individual instrument level or specific to clinical assessment of frailty, […]
Read MoreBy Pat Anson Pain News Network Editor An experimental non-opioid pain reliever gives long-term relief for chronic low back pain, but questions remain about joint damage and other side effects from the drug, according to a large new study. Tanezumab is a humanized monoclonal antibody that targets nerve growth factor (NGF), a protein in the […]
Read MoreAUTHORS: Yeoh, Cindy B. MD et al Anesthesia & Analgesia: July 2020 – Volume 131 – Issue 1 – p 16-23 Abstract The novel coronavirus disease 2019 (COVID-19) was first reported in China in December 2019. Since then, it has spread across the world to become one of the most serious life-threatening pandemics since the […]
Read MoreAuthor: Michael Walter Cardiovascular Business News A single dose of selatogrel can safely provide heart attack patients with a “profound, rapid” antiplatelet response, according to a new study published in the Journal of the American College of Cardiology. There are multiple P2Y12 receptor antagonists currently available, the authors explained, but the antiplatelet effect often takes too long to […]
Read MoreBy LORI HINNANT, CARLEY PETESCH and BOUBACAR DIALLO AP News Guinea’s best hope for coronavirus patients lies inside a neglected yellow shed on the grounds of its main hospital: an oxygen plant that has never been turned on. The plant was part of a hospital renovation funded by international donors responding to the Ebola crisis […]
Read MoreAuthors: Justin S. Liberman, M.D., M.P.H. et al Anesthesiology 7 2020, Vol.133, 41-52. Background: A nonroutine event is any aspect of clinical care perceived by clinicians or trained observers as a deviation from optimal care based on the context of the clinical situation. The authors sought to delineate the incidence and nature of intraoperative nonroutine events during […]
Read MoreAuthor: Michael Walter Cardiovascular Business News Venous thromboembolism (VTE) is a common complication among hospitalized patients, one that leads to longer lengths of stay and costs health systems up to $10 billion annually. The American Heart Association (AHA) has called for healthcare providers to cut hospital-acquired VTE by 20% in the next 10 years, publishing […]
Read MoreAUTHORS: Hayter, Ryan R. BS et al Anesthesia & Analgesia: April 2020 BACKGROUND: Helping patients to understand relative risks is challenging. In discussions with patients, physicians often use numbers to describe hazards, make comparisons, and establish relevance. Patients with a poor understanding of numbers—poor “health numeracy”—also have difficulty making decisions and coping with chronic conditions. […]
Read MoreAUTHORS: Berkow, Lauren MD, FASA et al Anesthesia & Analgesia: July 2020 – Volume 131 – Issue 1 – p e41-e43 To the Editor Coronavirus 2019 (COVID-19) puts patients at increased risk of experiencing unplanned extubation (UE), and both UE and subsequent reintubation put providers at increased risk of viral contamination. The increased patient surge […]
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