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Uncategorized Published - 17 November, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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Uncategorized Published - 14 November, 2025    By - Dr Clemens
Double trouble? The pharmacological pitfalls of mixing local anaesthetics

Authors: Michele Carella et al. Source: European Journal of Anaesthesiology 42(12):1043-1045, December 2025. DOI: 10.1097/EJA.0000000000002269 SummaryThis editorial commentary by Carella et al. reviews a randomized controlled trial by Yousef et al. that rigorously re-examined a longstanding but poorly supported practice in regional anesthesia—the admixture of amide-type local anesthetics (LAs) such as lidocaine and ropivacaine. The […]

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Uncategorized Published - 14 November, 2025    By - Dr Clemens
Time to Reconsider Tramadol for Chronic Pain?

Author: Carla Cantor Medscape BMJ Evidence-Based Medicine. Tramadol, a commonly prescribed opioid often viewed as a safer option for chronic pain, provided limited pain relief while increasing the risk for serious side effects, results of a new analysis showed. In a systematic review and meta-analysis, investigators found that tramadol offered clinically insignificant pain relief, while […]

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Uncategorized Published - 14 November, 2025    By - Dr Clemens
Intraoperative Cardiac Events in Pediatric Patients with Congenital Heart Disease Undergoing Noncardiac Procedures

Authors: Nasr, Viviane G. et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005783 This multicenter registry study characterized the incidence and predictors of intraoperative cardiac events in pediatric patients with congenital heart disease (CHD) undergoing noncardiac procedures. While previous studies focused primarily on mortality, this analysis—drawing from seven U.S. centers—specifically examined real-time intraoperative hemodynamic and cardiac […]

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Uncategorized Published - 14 November, 2025    By - Dr Clemens
Minimal clinically important changes of patient-reported outcome measures for acute post-surgical pain

Authors: Vollert, Jan et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005792 This large multicenter European study established reference values for the minimal clinically important difference (MCID) in postoperative pain and physical function using patient-reported outcome measures (PROMs). The MCID defines the smallest change in a score that patients perceive as meaningful—crucial for interpreting clinical trial […]

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Uncategorized Published - 14 November, 2025    By - Dr Clemens
Brain Retraining Yields Lasting Relief of Chronic Back Pain

Author: Megan Brooks Medscape  JAMA Psychiatry. Psychological therapy that changes an individual’s beliefs about pain can provide lasting relief for chronic back pain (CBP), long-term follow-up results of a randomized controlled trial showed. More than half of those who received the brain-focused pain reprocessing therapy (PRT) reported being nearly or completely pain-free 5 years later, […]

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Uncategorized Published - 14 November, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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Uncategorized Published - 13 November, 2025    By - Dr Clemens
Plasma fibrinogen level and severe bleeding in cardiac surgery

Authors: A Talvasto et al. Source: Canadian Journal of Anesthesia / Journal canadien d’anesthésie, (2025) October 30; DOI: 10.1007/s12630-025-03046-7 SummaryThis observational post-hoc analysis of the ALBICS trial examined 1,386 patients undergoing on-pump cardiac surgery to determine how plasma fibrinogen levels, both before and after cardiopulmonary bypass (CPB), relate to the risk of severe bleeding and […]

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Uncategorized Published - 13 November, 2025    By - Dr Clemens
Regional anesthesia and functional outcomes after anterior cruciate ligament reconstruction surgery in adolescent patients: Society of Pediatric Anesthesia Improvement Network (SPAIN)

Authors: (Multicenter Adolescent ACL Registry Investigators) BMJ Journals Regional Anesthesia & Pain Medicine This multicenter prospective observational study investigated the relationship between regional anesthesia and postoperative functional recovery in adolescents undergoing anterior cruciate ligament (ACL) reconstruction. While peripheral nerve blocks are widely used for perioperative analgesia, their potential effect on longer-term function and rehabilitation outcomes […]

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Uncategorized Published - 13 November, 2025    By - Dr Clemens
Revisiting infusion rate limitations for continuous lumbar plexus blocks in children and adolescents with 0.2% ropivacaine: a pharmacokinetic analysis

Authors: Sunder, Rani A. et al. Anesthesiology September 2025 | DOI: 10.1097/ALN.0000000000005775 This prospective pharmacokinetic study examined the safety and dosing parameters of continuous lumbar plexus blocks using 0.2% ropivacaine in pediatric patients. Although lumbar plexus blocks are effective for postoperative analgesia in children, limited pharmacokinetic data have restricted infusion rates due to concerns about […]

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