AUTHORS: Hunsberger, Joann B. MD, MS et al Anesthesia & Analgesia: September 2020 – Volume 131 – Issue 3 – p 866-875 BACKGROUND: The epidemic of nonmedical use of prescription opioids (NMUPOs) has been fueled in part by the availability of leftover, legitimately prescribed opioids. In children, outpatient urological procedures are among the most common […]
Read MoreAUTHORS: i, Jiafu MD et al Anesthesia & Analgesia: September 2020 – Volume 131 – Issue 3 – p 935-942 BACKGROUND: The misuse of opioids stems, in part, from inadequate knowledge of molecular interactions between opioids and opioid receptors. It is still unclear why some opioids are far more addictive than others. The κ-opioid receptor […]
Read MoreDG Alert A study published in the Journal of Clinical Endocrinology & Metabolism shows a 13.1% rate of thyroid dysfunction among patients with predominantly mild-to-moderate coronavirus disease 2019 (COVID-19). “There may be a direct effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on thyroid function, potentially leading to exacerbation of pre-existing autoimmune thyroid disease. Low free […]
Read MoreDG Alerts A study published in Science Advances reports on the ability of baricitinib, a JAK/STAT pathway inhibitor, to inhibit viral entry and reduce inflammatory markers in coronavirus disease 2019 (COVID-19) patients, reducing mortality risk by 71% among patients with moderate-severe COVID-19 pneumonia. In addition, the study shows that baricitinib prevents the type-1 interferon (IFN) mediated increase […]
Read MoreAUTHORS: Qin, Caroline X. BS et al Anesthesia & Analgesia: September 2020 – Volume 131 – Issue 3 – p 901-908 BACKGROUND: Patients requiring extracorporeal membrane oxygenation (ECMO) support are critically ill and have substantial transfusion requirements, which convey both risks and benefits. A retrospective analysis was conducted to assess the association between blood component […]
Read MoreAUTHORS: Gurunathan, Usha MBBS, MD, M Epi, FANZCA et al Anesthesia & Analgesia: September 2020 – Volume 131 – Issue 3 – p 741-750 BACKGROUND: There is a concern that midazolam, when used as a component of sedation for colonoscopy, may impair cognition and prolong recovery. We aimed to identify whether midazolam produced short- and […]
Read MoreAUTHORS: Galvagno, Samuel M. Jr DO, PhD, FCCM et al Anesthesia & Analgesia: September 2020 – Volume 131 – Issue 3 – p 754-761 BACKGROUND: Many believe obesity is associated with higher rates of mortality in the critically ill. The purpose of this retrospective observational study is to evaluate the association between body mass index […]
Read MoreAuthor: Kim Hathaway, MSN, CPHRM The Doctors Company Physicians have embraced smartphone technology, with the vast majority using phones to communicate via text messages and access medical information. The attraction is obvious: Smartphone applications place libraries full of information at users’ fingertips—including drug alerts (such as PDR.net) that are literally a click away. Texting via […]
Read MoreAuthor: Michael Walter Cardiovascular Business News COVID-19 patients who experience a stroke face a much greater risk of severe disability or death, according to a new study published in the Journal of Neurology, Neurosurgery & Psychiatry. The new analysis focused on 81 hospitalized COVID-19 patients who experienced an ischemic stroke and five who experienced an intracerebral […]
Read MoreAuthor: Michael Walter Cardiovascular Business News Marijuana use is associated with a greater risk of cardiovascular complications following percutaneous coronary intervention (PCI) procedures, according to new findings to be presented at the American Heart Association’s Scientific Sessions 2020 virtual meeting. A separate study, scheduled to be presented at the same meeting, found that acute myocardial […]
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