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Uncategorized Published - 3 February, 2021    By - Dr Clemens
n assessment of perioperative respiratory adverse events and difficult intubation in pediatric patients with trisomy 21

DG Journal Club AUTHORS: Taylor Graber, Paola Baskin et al. Paediatr Anaesth. 2021 INTRODUCTION Several prior studies have demonstrated an association between trisomy 21 and airway-related anesthetic complications. However, there is a paucity of large clinical studies characterizing the airway challenges associated with trisomy 21. In this analysis we examine anesthetic related airway complications in […]

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Uncategorized Published - 3 February, 2021    By - Dr Clemens
Magnetic resonance imaging of cerebrospinal fluid spread in the epidural space correlates with the severity of postdural puncture headache in obstetric patients

DG Journal Club AUTHORS: Iftikhar Ahmed, Amer Majeed et al. Eur J Anaesthesiol. 2021 BACKGROUND Currently, performing an epidural blood patch (EBP) for postdural puncture headache (PDPH) remains a subjective clinical decision. An evidence-based protocol may be of value in identifying women at high risk of developing a severe PDPH. OBJECTIVE To investigate a potential […]

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Uncategorized Published - 3 February, 2021    By - Dr Clemens
Predicting Perioperative Respiratory Adverse Events in Children With Sleep-Disordered Breathing

AUTHORS: Pehora, Carolyne RN, MN et al Anesthesia & Analgesia: September 2020 BACKGROUND: No evidence currently exists to quantify the risk and incidence of perioperative respiratory adverse events (PRAEs) in children with sleep-disordered breathing (SDB) undergoing all procedures requiring general anesthesia. Our objective was to determine the incidence of PRAEs and the risk factors in […]

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Uncategorized Published - 3 February, 2021    By - Dr Clemens
The outcome of epidural injections in lumbar radiculopathy is not dependent on the presence of disc herniation on MRI

DG Journal Club AUTHORS: E J A Verheijen, A G Munts et al. World Neurosurg. 2021 Jan OBJECTIVE Lumbar radiculopathy is a condition with major physical, social and economic consequences. Despite its favourable prognosis the burden can be significant. In this study, we aimed to determine the value of MRI and the efficacy of transforaminal […]

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Uncategorized Published - 3 February, 2021    By - Dr Clemens
Laryngeal Injury and Upper Airway Symptoms After Endotracheal Intubation During Surgery

AUTHORS: Brodsky, Martin B. PhD, ScM, CCC-SLP et al Anesthesia & Analgesia: November 2020  Abstract Laryngeal injury from intubation can substantially impact airway, voice, and swallowing, thus necessitating multidisciplinary interventions. The goals of this systematic review were (1) to review the types of laryngeal injuries and their patient-reported symptoms and clinical signs resulting from endotracheal […]

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Uncategorized Published - 2 February, 2021    By - Dr Clemens
Early Versus Late Tracheostomy in Patients With Acute Traumatic Spinal Cord Injury

AUTHORS: Mubashir, Talha MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 384-394 BACKGROUND:  Acute traumatic spinal cord injuries (SCIs) often result in impairments in respiration that may lead to a sequelae of pulmonary dysfunction, increased risk of infection, and death. The optimal timing for tracheostomy in patients […]

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Uncategorized Published - 2 February, 2021    By - Dr Clemens
A Continuous Noninvasive Method to Assess Mixed Venous Oxygen Saturation

AUTHORS: Karlsson, Jacob MD, PhD et al Anesthesia & Analgesia: September 2020 BACKGROUND: Mixed venous oxygen saturation (SvO2) is important when evaluating the balance between oxygen delivery and whole-body oxygen consumption. Monitoring SvO2 has so far required blood samples from a pulmonary artery catheter. By combining volumetric capnography, for measurement of effective pulmonary blood flow, with […]

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Uncategorized Published - 2 February, 2021    By - Dr Clemens
A Comparison of the Required Bronchial Cuff Volume Obtained by 2 Cuff Inflation Methods, Capnogram Waveform-Guided Versus Pressure-Guided

AUTHORS: Yamada, Yuko MD et al Anesthesia & Analgesia: September 2020 BACKGROUND: Double-lumen endobronchial tubes (DLTs) are used for one-lung ventilation (OLV) during thoracic surgery. Overinflation into the bronchial cuff causes damage to the tracheobronchial mucosa, whereas underinflation leads to an incomplete collapse of the nonventilated lung or incomplete ventilation of the ventilated lung. However, […]

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Uncategorized Published - 2 February, 2021    By - Dr Clemens
Association Among Preoperative Cognitive Performance, Regional Cerebral Oxygen Saturation, and Postoperative Delirium in Older Portuguese Patients

AUTHORS: Susano, Maria J. MD et al Anesthesia & Analgesia: September 2020 BACKGROUND: Postoperative delirium is common among older patients and preoperative identification of high-risk patients is widely recommended. The aim of this study was to assess whether preoperative cognitive performance using brief screening tools or regional cerebral oxygen saturation (SctO2) was associated with the […]

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Uncategorized Published - 2 February, 2021    By - Dr Clemens
Regeneron’s antibody cocktail effective in preventing Covid-19, company says

By Reuters The antibody cocktail is authorized by the FDA as a treatment for patients diagnosed with Covid-19. Pharmaceuticals said on its antibody cocktail was effective in preventing Covid-19 in people exposed to those infected with the new coronavirus, based on interim results from a late-stage study. The two-antibody cocktail, REGEN-COV, caused a 100 percent […]

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