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AUTHORS: O’Bryan, Liam J. MD et al Anesthesia & Analgesia: August 2021 BACKGROUND: The perioperative inflammatory response may be implicated in adverse outcomes including neurocognitive dysfunction and cancer recurrence after oncological surgery. The immunomodulatory role of anesthetic agents has been demonstrated in vitro; however, its clinical relevance is unclear. The purpose of this meta-analysis was to […]
Read MoreAuthors: Paul S. Myles, M.B.B.S., M.P.H., M.D., D.Sc., F.C.A.I., F.A.N.Z.C.A., F.R.C.A., F.A.H.M.S et al Anesthesiology August 2021. Dexamethasone is a commonly used drug in anesthesia and surgery. The purported beneficial effects are diverse, especially for the prophylaxis and treatment of postoperative nausea and vomiting, but the optimal dose and the clinical implications of potential side […]
Read MoreAuthor: Jessica Kim Cohen Modern Healthcare Magnets in Apple’s latest smartphone, the iPhone 12, can trigger a setting in some implantable cardiac devices that temporarily disable the devices, according to Food and Drug Administration researchers. The study, published in the journal Heart Rhythm this week, reinforces existing recommendations from the FDA urging patients to keep some consumer electronic devices […]
Read MoreAuthor: Beth JoJack Medical News Today Patients who reported experiencing widespread pain had an increased incidence of all-cause dementia, Alzheimer’s disease, and stroke. This increased risk is independent of factors such as age, health, or sociodemographic circumstance. Researchers analyzed data from 2,464 participants of the Framingham Offspring Study Cohort, who underwent examination by health practitioners […]
Read MoreDG Journal Club AUTHORS: Melissa M Masaracchia, Rani A Sunder et al. Paediatr Anaesth. 2021 Aug Ultrasound-guided nerve blocks have revolutionized the way we provide regional anesthesia. By providing effective perioperative pain control, regional anesthesia reduces opioid consumption, decreases length of stay, and increases patient/parental satisfaction. However, error traps (circumstances that lead to erroneous actions) […]
Read MoreAUTHORS: Ye, Yingchao MD et al Anesthesia & Analgesia: August 9, 2021 BACKGROUND: Cardiotoxicity can be induced by the commonly used amide local anesthetic, bupivacaine. Bupivacaine can inhibit protein kinase B (AKT) phosphorylation and activated adenosine monophosphate–activated protein kinase alpha (AMPKα). It can decouple mitochondrial oxidative phosphorylation and enhance reactive oxygen species (ROS) production. Apelin enhances […]
Read MoreAuthor: Cardiac anesthesiologist Most cardiac surgery (CS) programs mandate that a patient ingest nothing by mouth after midnight for surgery the following day, or at the very least, fast for 6 to 8 hours from the intake of a solid meal before elective cardiac surgery. Several randomized clinical trials have demonstrated, however, that nonalcoholic clear fluids […]
Read MoreAuthor: Cardiac Anesthesiologist Generally, in obese patients, the blood distributes more to nonadipose than to adipose tissues, resulting in higher plasma drug concentrations in obese patients with mg/kg dosing than in normal patients with less adipose mass. Furthermore, propofol clearance increases because of the increased liver volume and liver blood flow associated with obesity (and increased cardiac […]
Read MoreThis is for our readers who treat pain patients. Author: Jenna Fletcher Medical News Today Many preventive migraine medications exist. Some examples include angiotensin-converting enzyme (ACE) inhibitors, anticonvulsants, beta-blockers, and calcium channel blockers. Not every medication is right for every person, so individuals should always talk with a doctor to determine which migraine prevention method might work […]
Read MoreAuthor: Richard Novak, MD The Anesthesia Consultant What is a difficult anesthetic? Most people have no real idea what anesthesiologists do. Many imagine an anesthesiologist’s job is to give a patient some “gas” which to keep the patient asleep, while the surgeon (the real doctor) heals the patient. This image is oversimplified and wrong. Anesthesiologists […]
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