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Uncategorized Published - 9 November, 2021    By - Dr Clemens
Comparison of Percentage Prolonged Times to Tracheal Extubation Between a Japanese Teaching Hospital and One in the United States, Without and With a Phase I Postanesthesia Care Unit

AUTHORS: Sugiyama, Daisuke MD, PhD et al  Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1206-1214 BACKGROUND:  Prolonged times to tracheal extubation are those from end of surgery (dressing on the patient) to extubation 15 minutes or longer. They are so long that others in the operating room (OR) generally have […]

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Uncategorized Published - 9 November, 2021    By - Dr Clemens
The Effect of Low-Dose Intraoperative Ketamine on Closed-Loop-Controlled General Anesthesia

AUTHORS: Napoleone, Gabby BSc et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1215-1224 BACKGROUND:  Closed-loop control of propofol-remifentanil anesthesia using the processed electroencephalography depth-of-hypnosis index provided by the NeuroSENSE monitor (WAVCNS) has been previously described. The purpose of this placebo-controlled study was to evaluate the performance (percentage time within […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Driving Pressure–Guided Individualized Positive End-Expiratory Pressure in Abdominal Surgery:

AUTHORS: Zhang, Chengmi MD, PhD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1197-1205 BACKGROUND:  The optimal positive end-expiratory pressure (PEEP) to prevent postoperative pulmonary complications (PPCs) remains unclear. Recent evidence showed that driving pressure was closely related to PPCs. In this study, we tested the hypothesis that an […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Neurocognitive, Quality of Life, and Behavioral Outcomes for Patients With Covert Stroke After Cardiac Surgery

AUTHORS: Lewis, Choy MD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1187-1196 BACKGROUND:  Asymptomatic brain ischemic injury detected with diffusion-weighted magnetic resonance imaging (DWI) is reported in more than one-half of patients after cardiac surgery. There are conflicting findings on whether DWI-detected covert stroke is associated with neurocognitive […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Survey of Practice Pattern in Patients With Heparin-Induced Thrombocytopenia Requiring Cardiopulmonary Bypass

AUTHORS: Wanat-Hawthorne, Alycia MD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1180-1186 BACKGROUND:  Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse reaction to heparin. Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) are routinely anticoagulated with heparin before the initiation of bypass. Heparin is contraindicated, however, in patients with […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Relationship Between the Loaded Pressure and Flow Rate of Packed Red Blood Cells and Various Infusion Solutions in Normal Infusion Lines and Catheters

AUTHORS: Miyoshi, Hirotsugu MD, PhD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1107-1115   BACKGROUND:  We investigated the relationship between the loaded pressure and flow rate in various catheters and the entire infusion line including the catheters, in several infusion solutions and packed red blood cells. METHODS: We […]

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Uncategorized Published - 8 November, 2021    By - Dr Clemens
Anesthetic Effects on the Progression of Parkinson Disease in the Rat DJ-1 Model

AUTHORS: Xu, Daniel A. BS et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1140-1151 BACKGROUND:  Parkinson disease is a chronic and progressive movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The causes of Parkinson disease are not clear but may involve […]

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Uncategorized Published - 5 November, 2021    By - Dr Clemens
Association of Delirium during Critical Illness With Mortality

AUTHORS: Hughes, Christopher G. MD, MS et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1152-1161 BACKGROUND:  The temporal association of delirium during critical illness with mortality is unclear, along with the associations of hypoactive and hyperactive motoric subtypes of delirium with mortality. We aimed to evaluate the relationship of […]

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Uncategorized Published - 5 November, 2021    By - Dr Clemens
Migraine headaches while breastfeeding: Causes

Author: Joanne Lewsley MedicalNewsToday Migraine affects millions of people in the United States. Although the condition can sometimes improve during pregnancy, it may worsen in the postpartum period and sometimes while breastfeeding. According to the American Migraine Foundation, migraine is a debilitating condition that affects around 39 million people in the U.S. Chronic migraine, when a person has […]

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Uncategorized Published - 5 November, 2021    By - Dr Clemens
A Systematic Review and Meta-Analysis of Preoperative Frailty Instruments Derived From Electronic Health Data

AUTHORS: Alkadri, Jamal MD et al Anesthesia & Analgesia: November 2021 – Volume 133 – Issue 5 – p 1094-1106 BACKGROUND:  Frailty is a strong predictor of adverse outcomes in the perioperative period. Given the increasing availability of electronic medical data, we performed a systematic review and meta-analysis with primary objectives of describing available frailty instruments […]

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