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DG Journal Club AUTHORS: Aaron St-Laurent, Zofia Zysman-Colman et al. Paediatr Anaesth. 2021 Dec 5 Children with neruromuscular, chronic neurologic and chest wall diseases are at increased risk of post-operative respiratory complications including atelectasis, pneumonia, respiratory failure with the possible need for reintubation or even tracheostomy. These complications negatively impact patient outcomes, including increased healthcare […]
Read MoreAuthor: Kathleen davis FNP MedicalNewsToday Ketamine is a medication that doctors use as an anesthetic to induce loss of consciousness. Effects include sedation and reduced sensation of pain. The drug is a Schedule III non-narcotic that the Food and Drug Administration (FDA) has approved for use only as a general anesthetic. However, doctors sometimes prescribe it for “off-label” […]
Read MoreAUTHORS: Pensier, Joris MD et al Anesthesia & Analgesia: November 2021 Export BACKGROUND: In critically ill patients, warnings about a risk of death and acute kidney injury (AKI) with hydroxyethyl starch (HES) solutions have been raised. However, HES solutions may yet have a role to play in major abdominal surgery. This meta-analysis and trial sequential analysis […]
Read MoreAUTHORS: Kouz, Karim MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Cardiac output is an important hemodynamic variable and determines oxygen delivery. In contrast to blood pressure, cardiac output is rarely measured even in high-risk surgical patients, suggesting that clinicians consider blood pressure to be a reasonable indicator of systemic blood flow. However, the relationship […]
Read MoreAuthors: Nadav Y. Schacham, M.D. et al Anesthesiology November 2021. Background Age- and sex-specific reference nomograms for intraoperative blood pressure have been published, but they do not identify harm thresholds. The authors therefore assessed the relationship between various absolute and relative characterizations of hypotension and acute kidney injury in children having noncardiac surgery. Methods The […]
Read MoreAuthors: Ricardo Alvarez-Jimenez, M.D., Ph.D. et al Anesthesiology December 2021. Background Numerous pharmacokinetic models have been published aiming at more accurate and safer dosing of dexmedetomidine. The vast majority of the developed models underpredict the measured plasma concentrations with respect to the target concentration, especially at plasma concentrations higher than those used in the original […]
Read MoreDG Alerts Among patients with severe coronavirus disease 2019 (COVID-19), use of high-flow oxygen through a nasal cannula significantly decreased need for mechanical ventilation support and time to clinical recovery compared with conventional low-flow oxygen therapy, according to a study published in JAMA. From August 2020 to January 2021, 220 patients with respiratory distress and a […]
Read MoreAuthors: Cecilia Canales, M.D., M.P.H. et al Anesthesiology December 2021. Background Frailty is increasingly being recognized as a public health issue, straining healthcare resources and increasing costs to care for these patients. Frailty is the decline in physical and cognitive reserves leading to increased vulnerability to stressors such as surgery or disease states. The goal […]
Read MoreAuthors: Pandit, Sujit K. MD; Loberg, Katherine W. BS; Pandit, Uma A. MD Anesthesia & Analgesia: November 2000 – Volume 91 – Issue 5 – p 1308 This also gives us an opportunity to clarify the prevalent ambiguity about types of “clear” liquid that are allowed 2–3 h before elective surgery. Dr. Sosis has asked a […]
Read MoreAUTHORS: Bash, Lori D. PhD, MPH et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1437-1450 BACKGROUND: Neuromuscular blockade (NMB) is a critical part of many surgical procedures. Data on practice patterns of NMB agents (NMBAs) and NMB reversal in recent years in the US ambulatory surgical care setting are […]
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