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AUTHORS: Dermot P. Maher, M.D., M.S., M.H.S. et al Anesthesiology June 2022. Background The authors estimate the probability of successful development and duration of clinical trials for medications to treat neuropathic and nociceptive pain. The authors also consider the effect of the perceived abuse potential of the medication on these variables. Methods This study uses […]
Read MoreAUTHORS: Friedrichson, Benjamin et al European Journal of Anaesthesiology: May 2022 – Volume 39 – Issue 5 – p 445-451 BACKGROUND In the context of the coronavirus disease 2019 (COVID-19) pandemic, many retrospective single-centre or specialised centre reports have shown promising mortality rates with the use of extracorporeal membrane oxygenation (ECMO) therapy. However, the mortality rate […]
Read MoreAUTHORS: Kristian Kjaer-Staal Petersen et al Eur J Pain. 2022 May 31 BACKGROUND Duloxetine is indicated in the management of pain in osteoarthritis. Evidence suggests that duloxetine modulate central pain mechanisms and cognitive factors, and these factors are assumed contributing to the analgesic effect. This proof-of-mechanism, randomized, placebo-controlled, crossover, double-blinded trial evaluated the effect of […]
Read MoreAuthor: Brian Thomas, JD et al Anesthesia Patient Safety Foundation Volume 37, No. 2 June 2022 Administration of sevoflurane at low-flow rates remains a controversial practice due to the low-flow limits described in the Food and Drug Administration’s (FDA) required labeling. Specifically, the labeling in the United States requires no less than 1 L/min for […]
Read MoreAuthors: Kimberley Lewis et al Intensive Care Med. 2022 Jun 1 Conventional gabaminergic sedatives such as benzodiazepines and propofol are commonly used in mechanically ventilated patients in the intensive care unit (ICU). Dexmedetomidine is an alternative sedative that may achieve lighter sedation, reduce delirium, and provide analgesia. Our objective was to perform a comprehensive systematic […]
Read MoreAuthors: Jeffrey M. Feldman, MD, MSE; Samsun Lampotang, PhD, FSSH, FAIMBE Anesthesia Patient Safety Foundation Volume 37, No. 2 June 2022 The benefits of low-flow anesthesia are well established and include reduced inhaled anesthetic waste, decreased cost, and fewer greenhouse gas effects.1 For the individual patient, low-flow anesthesia reduces loss of heat and humidity from the […]
Read MoreAuthor: Anna Smith MedicalNewsToday Fibromyalgia is a condition that causes a person to experience chronic pain. Bipolar disorder is a mental health condition that can cause extreme shifts in mood. Research suggests that there may be an association between the two conditions. Having fibromyalgia is often associated with having an emotional or affective disorder, as well. […]
Read MoreAuthors: Lawrence Caruso, MD; Samsun Lampotang, PhD, FSSH, FAIMBE; Nikolaus Gravenstein, MD Anesthesia Patient Safety Foundation Volume 37, No. 2 June 2022 SUMMARY:The Anesthesia Patient Safety Foundation (APSF) Committee on Technology recently advocated for neuromuscular transmission (NMT) monitoring when an intermediate-acting muscle relaxant is used. Moving from clinical monitoring to train-of-four NMT monitoring represents the […]
Read MoreAuthor: Kristina Lavarone MedicalNewsToday Soma is a medication that doctors prescribe for treating muscle pain and discomfort. It has sedative effects and can be habit-forming. Doctors recommend taking Soma for short periods to avoid dependence on the drug. Soma is also a drug that some people can take recreationally. It has sedative effects and alters […]
Read MoreAuthor: Mary West MedicalNewsToday “Transforming migraine” is not a medical term. However, “transformed migraine” is a term that doctors used in the past to describe migraine episodes that had gone from being occasional to frequent. Today, doctors call this process the “chronification” of migraine. When a person experiences headaches for a minimum of 15 days out of every month […]
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