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Uncategorized Published - 20 July, 2022    By - Dr Clemens
Brain Health and the EEG: Toward Personalized Anesthesia Care for Older Patients

AUTHORS: Patrick L. Purdon, PhD et al  ASA Monitor May 2022, Vol. 86, 1–9. The brain under anesthesia is a marvel to behold. Although the electroencephalogram (EEG) is not a routine part of clinical anesthesia care, there is growing evidence that readily visible changes in the anesthesia-induced EEG are intimately linked to perioperative brain health. Induction […]

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Uncategorized Published - 20 July, 2022    By - Dr Clemens
Age-Specific Clinical Features of Pediatric Malignant Hyperthermia

AUTHORS: Otsuki, Sachiko MD, PhD et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 128-135 BACKGROUND: Malignant hyperthermia (MH) is an inherited muscle disorder induced by volatile anesthetics and depolarizing muscle relaxants. While the incidence of MH is high in young, there are few reports on the clinical features of […]

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Uncategorized Published - 20 July, 2022    By - Dr Clemens
Is Obesity Associated With Better Liver Transplant Outcomes?

AUTHORS: Du, Austin L. BS et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 118-127 BACKGROUND: The rise in obesity in the United States, along with improvements in antiviral therapies, has led to an increase in the number of obese patients receiving liver transplants. Currently, obesity is a relative contraindication […]

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Uncategorized Published - 20 July, 2022    By - Dr Clemens
Association Between Aspirin Use and Sepsis Outcomes

AUTHORS: Hsu, Wan-Ting MS et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 110-117 BACKGROUND: Aspirin has anti-inflammatory and antiplatelet activities and directly inhibits bacterial growth. These effects of aspirin may improve survival in patients with sepsis. We retrospectively reviewed a large national health database to test the relationship between […]

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Uncategorized Published - 19 July, 2022    By - Dr Clemens
Continuous Titration of Inspired Oxygen Using Oxygen Reserve Index to Decrease Oxygen Exposure During One-Lung Ventilation

AUTHORS: Yang, Mikyung MD, PhD et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 91-99 BACKGROUND:  A high fraction of inspired oxygen (Fio2) is administered during one-lung ventilation (OLV). However, a high Fio2 is not physiologic and may lead to various complications. We hypothesized that continuous titration of Fio2 using the oxygen […]

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Uncategorized Published - 19 July, 2022    By - Dr Clemens
Pulse Wave Analysis Using the Pressure Recording Analytical Method to Measure Cardiac Output in Pediatric Cardiac Surgery Patients

AUTHORS: Greiwe, Gillis MD et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 71-78 BACKGROUND: Cardiac output (CO) is a key determinant of oxygen delivery, but choosing the optimal method to obtain CO in pediatric patients remains challenging. The pressure recording analytical method (PRAM), implemented in the MostCareUp system (Vygon), […]

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Uncategorized Published - 19 July, 2022    By - Dr Clemens
Effects of Etco2 on the Minimum Alveolar Concentration of Sevoflurane that Blunts the Adrenergic Response to Surgical Incision

AUTHORS: Wu, Zhijie MD et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 62-70 BACKGROUND: CO2 has anesthetic potency and effectively influences the circulatory system. We investigated the effects of Etco2 on the minimum alveolar concentration of sevoflurane that blunts the adrenergic response to surgical incision (MAC-BAR) in patients undergoing radical surgery […]

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Uncategorized Published - 19 July, 2022    By - Dr Clemens
Chronic migraine: Common anesthetic relieves pain in new study

Author: Ferdinand Lali, Ph.D. MedicalNewsToday A new observational study suggests that intravenous administration of the anesthetic agent lidocaine could help alleviate pain in individuals hospitalized with hard-to-treat chronic migraines. Nearly 88% of chronic migraine patients receiving intravenous lidocaine during hospitalization showed a reduction in pain intensity at discharge. This study paves the way for randomized […]

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Uncategorized Published - 18 July, 2022    By - Dr Clemens
Awake cardiac surgery using the novel pectoralis-intercostal-rectus sheath (PIRS) plane block and subxiphoid approach

DG Journal Club AUTHORS: Toscano Antonio, et al J Card Surg. 2022 Jun 4 BACKGROUND Postoperative pain after cardiac surgery is a very important issue and affects recovery, risk of postoperative complications and quality of life. The pain management has been traditionally based on intravenous opioids with growing evidence suggesting the use of opioid-free and […]

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Uncategorized Published - 18 July, 2022    By - Dr Clemens
Comparing the effects of peripheral nerve block and general anesthesia with general anesthesia alone on postoperative delirium and complications in elderly patients

DG Journal Club AUTHORS: Manabu Yoshimura, Hiroko Shiramoto, Mami Koga, Aya Yoshimatsu Reg Anesth Pain Med. 2022 May 30 INTRODUCTION The difference between the effects of peripheral nerve block (PNB) with general anesthesia (GA) and GA alone on the patients’ postoperative clinical outcomes remains unknown. We assessed whether there is a difference in postoperative delirium […]

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