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Uncategorized Published - 18 October, 2022    By - Dr Clemens
Analgesic Effectiveness and Dorsal Root Ganglia Protein Modulation of a Peripheral Adenosine Monophosphate Kinase Alpha Activator (O304) Following Lumbar Disk Puncture in the Mouse

AUTHORS: Das, Vaskar PhD et al Anesthesia & Analgesia: October 06, 2022 BACKGROUND: Disk herniation is a primary cause of radicular back pain. The purpose of this study was to evaluate the antiallodynic effective dose in 50% of the sample (ED50) and dorsal root ganglion (DRG) protein modulation of a peripheral direct adenosine monophosphate kinase alpha […]

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Uncategorized Published - 18 October, 2022    By - Dr Clemens
Caffeine and migraine: What is the link?

Author: Zia Sherrell MedicalNewsToday For some people, caffeine consumption can trigger migraine symptoms. However, others may find it helps ease their pain, especially in combination with other medications. Scientists are not sure why people have different reactions. Caffeine is a stimulant present in many beverages and foods, including coffee, tea, and chocolate. Many people consume it […]

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Uncategorized Published - 17 October, 2022    By - Dr Clemens
Age-Stratified Propofol Dosage for Pediatric Procedural Sedation and Analgesia

AUTHORS: van Dijk, Huib MD et al  Anesthesia & Analgesia: September 23, 2022 Background:  Procedural sedation and analgesia (PSA) for diagnostic and minimally invasive therapeutic procedures has become common practice in children of all ages. Based on our clinical experience, we suspected an inverse relation between age and dosage. However, a schedule for age-stratified propofol induction […]

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Uncategorized Published - 17 October, 2022    By - Dr Clemens
Trifascicular block with syncope triggered by preoperative mydriatic eye drops for cataract surgery

DG Journal Club Authors: V Vermot-Desroches, F Pollet-Villard J Fr Ophtalmol. 2022 Sep 19 We report the case of an 85-year-old patient who developed trifascicular block with syncope, triggered by preoperative eye drops for cataract surgery. This life-threatening situation reopens the debate over the necessity of having an anesthesiologist present during cataract surgery.

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Uncategorized Published - 17 October, 2022    By - Dr Clemens
Perioperative Gabapentin Use and In-Hospital Adverse Clinical Events Among Older Adults After Major Surgery

DG Journal Club AUTHORS: Chan Mi Park et al JAMA Intern Med. 2022 Sep 19 Importance Gabapentin has been increasingly used as part of a multimodal analgesia regimen to reduce opioid use in perioperative pain management. However, the safety of perioperative gabapentin use among older patients remains uncertain. Objective To examine in-hospital adverse clinical events […]

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Uncategorized Published - 17 October, 2022    By - Dr Clemens
The Impact of Inflammation and General Anesthesia on Memory and Executive Function in Mice

AUTHORS: Khodaei, Shahin HBSc et al  Anesthesia & Analgesia: September 30, 2022 BACKGROUND:  Perioperative neurocognitive disorders (PNDs) are complex, multifactorial conditions that are associated with poor long-term outcomes. Inflammation and exposure to general anesthetic drugs are likely contributing factors; however, the relative impact of each factor alone versus the combination of these factors remains poorly understood. […]

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Uncategorized Published - 17 October, 2022    By - Dr Clemens
Adults with ADHD may be twice as likely to develop cardiovascular diseases

This is so when we see a pt with ADHD preop we know of the increase risk. Author: Deep Shukla MedicalNewsToday A large population-based study in Sweden recently showed that individuals with attention deficit hyperactivity disorder (ADHD) were at a two-fold higher risk of all types of cardiovascular diseases than those without ADHD. Among adults […]

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Uncategorized Published - 14 October, 2022    By - Dr Clemens
Patterns of Use in Transesophageal Echocardiography for Liver Transplantation

Authors: W Jonathan Dunkman et al Semin Cardiothorac Vasc Anesth. 2022 Oct 6 Transesophageal echocardiography is frequently but not always used to guide anesthetic management during liver transplantation. We performed a systematic review of the literature to identify and summarize any studies reporting on the frequency and characteristics of TEE use for liver transplantation. Studies […]

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Uncategorized Published - 14 October, 2022    By - Dr Clemens
Effects of Goal-Directed Hemodynamic Therapy Using a Noninvasive Finger-Cuff Monitoring Device on Intraoperative Cerebral Oxygenation and Early Delayed Neurocognitive Recovery in Patients Undergoing Beach Chair Position Shoulder Surgery

AUTHORS: Lee, Chen-Tse MD et al  Anesthesia & Analgesia: September 22, 2022 BACKGROUND:  Perioperative cerebral desaturation events (CDEs) and delayed neurocognitive recovery are common among patients undergoing beach chair position (BCP) shoulder surgery and may be caused by cerebral hypoperfusion. This study tested the hypothesis that the application of goal-directed hemodynamic therapy (GDHT) would attenuate these […]

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Uncategorized Published - 14 October, 2022    By - Dr Clemens
Machine learning-based prediction of massive perioperative allogeneic blood transfusion in cardiac surgery

AUTHORS: Tschoellitsch, Thomas et al  European Journal of Anaesthesiology: September 2022 – Volume 39 – Issue 9 – p 766-773 BACKGROUND Massive perioperative allogeneic blood transfusion, that is, perioperative transfusion of more than 10 units of packed red blood cells (pRBC), is one of the main contributors to perioperative morbidity and mortality in cardiac surgery. Prediction […]

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