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Uncategorized Published - 1 November, 2022    By - Dr Clemens
The Next Viral Pandemic: Not a Question of If, But When and How

Author: Vetter, Thomas R. MD, MPH Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 900-902 “Those who cannot remember the past are condemned to repeat it.” —Jorge Agustín Nicolás Ruiz de Santayana y Borrás, known in English as George Santayana (1863–1952), Spanish-American philosopher, essayist, poet, and novelist In early January […]

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Uncategorized Published - 1 November, 2022    By - Dr Clemens
Characterization of 2 Different Prothrombin Complex Concentrates by Different Hemostatic Assays in an In Vitro Hemodilution Model

AUTHORS: Infanger, Lukas MD et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 1031-1040 BACKGROUND: Viscoelastically guided coagulation factor concentrate-based algorithms for the treatment of trauma-induced coagulopathy include the administration of prothrombin complex concentrates (PCCs). However, the exact role of PCC preparations in this context is a matter of debate. […]

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Uncategorized Published - 31 October, 2022    By - Dr Clemens
Total Intravenous Anesthesia Versus Inhaled Sevoflurane in Obstructive Sleep Apnea Surgery

AUTHORS: Leonard E Estephan et al Laryngoscope. 2022 Oct 14 OBJECTIVE Specific guidelines regarding an optimal general anesthesia (GA) approach to obstructive sleep apnea (OSA) patients remain undefined. Literature comparing the efficacy of total intravenous anesthesia (TIVA) and inhalational anesthesia in this population is sparse. We hypothesize that OSA patients receiving TIVA will experience reduced […]

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Uncategorized Published - 31 October, 2022    By - Dr Clemens
Pharynx volume derived from three-dimensional computed tomography is associated with difficult intubation in spinal deformity surgery

DG Journal Club AUTHORS: Xiaoyan Li, Bei An, Bailin Jiang, Shuai Xu Medicine (Baltimore). 2022 Oct 14; 101(41): e31139 Spinal abnormality surgery, including surgery for ankylosing spondylitis and idiopathic scoliosis, can present significant challenges to anesthesiologists because of the potential difficult airway. The bedside screening tests routinely used to detect difficult airways are highly variable. […]

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Uncategorized Published - 31 October, 2022    By - Dr Clemens
A case of unexpected intraoperative airway obstruction in a patient with an aneurysm of the ascending aorta and aortic arch

DG Journal Club AUTHORS: Jianming Yue, Leng Zhou, Peng Liang Anaesth Intensive Care. 2022 Oct 10 Upper airway compression is one of the clinical manifestations of thoracic aortic aneurysm, which is associated with poor prognosis and high mortality. A 44-year-old patient with ascending aortic and arch aneurysm who was scheduled for Bentall surgery and total […]

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Uncategorized Published - 31 October, 2022    By - Dr Clemens
Anesthesia in Low-Resourced Settings. Near Misses and Lessons Learned

Authors: G. Brock-Utne et al Anesthesiology September 2022. Physician training requires the highest intelligence quotient of all professions to assimilate the vast amounts of complex knowledge required. The most critical decision-making medical specialty is anesthesiology, which requires much art of practicing medicine. That art is acquired via experience from years of medical practice. Clinical experience can also be gleaned from studying […]

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Uncategorized Published - 31 October, 2022    By - Dr Clemens
Vitamin B1 may decrease the chances of migraine headaches

Author: Jessica Norris MedicalNewsToday Migraine headaches can be debilitating and difficult to treat. Researchers are still working to discover factors that influence migraine development and the best ways to treat and prevent these headaches. A​ recent study found that diets high in the B vitamin thiamine were associated with a decreased risk of migraine. Migraine […]

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Uncategorized Published - 28 October, 2022    By - Dr Clemens
Local anesthetic cardiac toxicity is mediated by cardiomyocyte calcium dynamics

Authors: Julia Plakhotnik, B.Sc. et at  Anesthesiology September 2022. Background Long-lasting local anesthetic use for perioperative pain control is limited by possible cardiotoxicity (e.g., arrhythmias and contractile depression), potentially leading to cardiac arrest. Off-target cardiac sodium channel blockade is considered the canonical mechanism behind cardiotoxicity, however, it does not fully explain the observed toxicity variability […]

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Uncategorized Published - 28 October, 2022    By - Dr Clemens
Post-cardiac Arrest Sedation Promotes Electroencephalographic Slow-wave Activity and Improves Survival in a Mouse Model of Cardiac Arrest

Authors: Takamitsu Ikeda, M.D., Ph.D. et al   Anesthesiology September 2022. Background Patients resuscitated from cardiac arrest are routinely sedated during targeted temperature management, while the effects of sedation on cerebral physiology and outcomes after cardiac arrest remain to be determined. We hypothesized that sedation would improve survival and neurological outcomes in mice after cardiac […]

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Uncategorized Published - 28 October, 2022    By - Dr Clemens
Marijuana, meth, cocaine and opiates all linked to heart rhythm issues

Author: Michael Walter Cardiovascular Business Marijuana, methamphetamine, cocaine and opiates are all associated with an increased risk of developing atrial fibrillation (AFib), according to new findings published in European Heart Journal.[1] “Though alcohol and tobacco smoking have each been associated with a heightened risk of AFib, relationships between other drug use and AFib are poorly understood,” […]

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