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Genixus™ Introduces Propofol as the First Product to be Delivered Within KinetiX™ Ready-to-Administer (RTA) Syringe Platform

Cardiovascular-related deaths in the US fall, but disparities remain

Source: asamonitor.pub/3AmcdYd A National Institutes of Health (NIH)-supported study found that cardiovascular-related deaths have declined over the past two decades, but disparities remain. Inequities are mostly driven by differences in race and ethnicity, geographic location, and access to care, among other factors. The findings, recently published in Circulation (Circulation July 2022), reviewed three papers. Each paper – published by […]

Ventilation Strategies During General Anesthesia for Noncardiac Surgery

AUTHORS: Bolther, Maria MD et al Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 971-985 BACKGROUND: The optimal ventilation strategy during general anesthesia is unclear. This systematic review investigated the relationship between ventilation targets or strategies (eg, positive end-expiratory pressure [PEEP], tidal volume, and recruitment maneuvers) and postoperative outcomes. METHODS: PubMed […]

Cite Share Favorites Permissions ORIGINAL RESEARCH ARTICLES: ORIGINAL CLINICAL RESEARCH REPORT Intraoperative Inspiratory Oxygen Fraction and Myocardial Injury After Noncardiac Surgery

AUTHORS: Pedersen, Sofie S. MD et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 1021-1030 BACKGROUND: Two trials reported that a high inspiratory oxygen fraction (Fio2) does not promote myocardial infarction or death. Observational studies can provide larger statistical strength, but associations can be due to unobserved confounding. Therefore, we […]

Emergency Airway Management Outside the Operating Room

AUTHORS: Karamchandani, Kunal MD, FCCP, FCCM et al  Anesthesia & Analgesia: September 2021 – Volume 133 – Issue 3 – p 648-662 Abstract Emergency airway management outside the operating room (OR) is often associated with an increased risk of airway related, as well as cardiopulmonary, complications which can impact morbidity and mortality. These emergent airways may […]

Severe Intraoperative Hyperglycemia and Infectious Complications After Elective Brain Neurosurgical Procedures

AUTHORS: Kulikov, Alexander MD, PhD et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 1082-1088 BACKGROUND: Postoperative infections after brain surgery are a serious complication potentially worsening the outcome of surgical treatment. Severe intraoperative hyperglycemia (SIH) contributes to both infectious and noninfectious postoperative complications. However, there are a lack of […]

Differential Perioperative Outcomes in Patients With Obstructive Sleep Apnea, Obesity, or a Combination of Both Undergoing Open Colectomy

AUTHORS: Stundner, Ottokar MD, MBA et al Anesthesia & Analgesia: September 2021 – Volume 133 – Issue 3 – p 755-764 BACKGROUND: An increasing body of evidence demonstrates an association between obstructive sleep apnea (OSA) and adverse perioperative outcomes. However, large-scale data on open colectomies are lacking. Moreover, the interaction of obesity with OSA is unknown. […]

Liver Fibrosis Marker and Postoperative Mortality in Patients Without Overt Liver Disease

AUTHORS: Zelber-Sagi, Shira PhD et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 957-966 BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) can progress to advanced fibrosis, which, in the nonsurgical population, is associated with poor hepatic and extrahepatic outcomes. Despite its high prevalence, NAFLD and related liver fibrosis may be overlooked […]

Efficacy of Preoperative Oral Midodrine in Preventing Hypotension After Spinal Anesthesia in Young Adults

AUTHORS: Alseoudy, Mahmoud Mohammed MD et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 1089-1096 BACKGROUND: Midodrine was effectively used for prophylaxis against hypotensive syndromes such as postural hypotension and intradialytic hypotension, and during the recovery phase of septic shock. In our study, we aimed to assess the efficacy of […]

Association Between Race and Opioid-Induced Respiratory Depression

AUTHORS: Sim, Ming Ann MBBS et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 1097-1105 BACKGROUND: Opioid-induced respiratory depression (OIRD) is common on the medical and surgical wards and is associated with increased morbidity and health care costs. While previous studies have investigated risk factors for OIRD, the role of […]