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Authors: Roger L. Royster, M.D. et al Anesthesiology December 2022, Vol. 137, 733–734. Hypoxic pulmonary vasoconstriction occurs when the microvasculature perfusing hypoxic alveoli vasoconstricts, diverting blood to oxygenated alveoli to match ventilation with perfusion. Hypoxic pulmonary vasoconstriction can occur within seconds and reach a maximum intensity within minutes of hypoxia developing. It appears to be triggered by […]
Read MoreAuthor: David O. Warner, M.D. Anesthesiology October 2022, Vol. 137, 484–508. Tobacco use will kill a projected 1 billion people in the 21st century in one of the deadliest pandemics in history. Tobacco use disorder is a disease with a natural history, pathophysiology, and effective treatment options. Anesthesiologists can play a unique role in fighting this […]
Read MoreAuthor: Igor Kissin, M.D., Ph.D. Anesthesiology October 2022. To the Editor: The state of general anesthesia is often presented with its analgesic component included. An example of this can be found in one of the classic definitions of the anesthetic state by Dr. Edmond Eger. He describes analgesia as an “unmeasurable component (the anesthetized patients cannot […]
Read MoreAuthors: Reed J. Yaras, DO, Jeffrey J. Bettinger, PharmD Practical Pain Management June 22,2022 These new recommendations are based on systematic reviews of the available scientific evidence and intend to provide clinicians with the knowledge they need to weigh the risks and benefits regarding the treatment of pain. When to Schedule Follow-Up Patients Prescribed Opioids […]
Read MoreAuthor: Deep Shukla MedicalNewsToday Due to the risk of addiction associated with the prolonged use of prescription opioids, there is an urgent need for non-opioid alternatives for the treatment of chronic pain. Drugs such as dexmedetomidine that bind to the norepinephrine alpha-2a (α2a) adrenergic receptor are effective analgesics, but their sedative effects limit their widespread […]
Read MoreBy E. Murray Joseph, M.D. Science History Publications/USA for Boston Medical Library, Sagamore Beach, 2001 . Pages: 255. ISBN-10: 0-88135-256-X. ISBN-13: 978-0881352566. Price: $150.00 (Hardcover). Price: $61.89 (Paperback). Science History Publications/USA for Boston Medical Library Kathryn Elizabeth McGoldrick, M.D., F.C.A.I. (Hon.) Anesthesiology December 2022, Vol. 137, 752–753. Joseph E. Murray, M.D. (1919 to 2012), was one […]
Read MoreDG Journal Club AUTHORS: Ingeborg de Rover et al Br J Anaesth. 2022 Oct 22 BACKGROUND Sedation techniques and drugs are increasingly used in children undergoing imaging procedures. In this systematic review and meta-analysis, we present an overview of literature concerning sedation of children aged 0-8 yr for magnetic resonance imaging (MRI) procedures using needle-free […]
Read MoreDG Journal Club AUTHORS: Alexa R Deemer, David L Furgiuele, Abhishek Ganta, Philipp Leucht J Orthop Trauma. 2022 Oct 17 OBJECTIVES To examine the efficacy of regional anesthesia with sedation only for a variety of hip fractures using the newly described lateral femoral cutaneous with over the hip Block (LOH Block). DESIGN Retrospective. SETTING Level-I […]
Read MoreAUTHORS: Salaün, Jean-Philippe MD, PhD et al Anesthesia & Analgesia: October 27, 2022 BACKGROUND: One in 7 children will need general anesthesia (GA) before the age of 3. Brain toxicity of anesthetics is controversial. Our objective was to clarify whether exposure of GA to the developing brain could lead to lasting behavioral and structural brain changes. […]
Read MoreAUTHORS: Jiang, Jia-Li MD et al Anesthesia & Analgesia: October 27, 2022 BACKGROUND: The effect of anesthesia regimens on postoperative delirium after on-pump cardiac valve surgery is yet undetermined. This study aimed to evaluate the effect of volatile anesthesia compared with propofol-based total intravenous anesthesia (TIVA) on the occurrence of delirium after on-pump cardiac valve surgery. […]
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