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Uncategorized Published - 15 February, 2023    By - Dr Clemens
GABAergic Signaling During Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model

Authors: Kimberly Howard-Quijano, M.D., M.S. et al  Anesthesiology January 2023. Background Neuraxial modulation, including spinal cord stimulation, reduces cardiac sympathoexcitation and ventricular arrhythmogenesis. There is an incomplete understanding of the molecular mechanisms through which spinal cord stimulation modulates cardiospinal neural pathways. We hypothesize that spinal cord stimulation reduces myocardial ischemia/reperfusion induced sympathetic excitation and ventricular […]

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Uncategorized Published - 15 February, 2023    By - Dr Clemens
How Physicians Frame Low Back Pain Affects Treatment Efficacy

Author: Avery Hurt Practical Pain Management Jan 2023 Low back pain is simultaneously one of the most common and vexing pain conditions physicians treat. According to the International Association for the Study of Pain (IASP), low back pain (LBP) is the leading cause of years lived with disability and is a major public health concern […]

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Uncategorized Published - 14 February, 2023    By - Dr Clemens
Nationwide Clinical Practice Patterns of Anesthesiology Critical Care Physicians

AUTHORS: Shaefi, Shahzad MD, MPH et al  Anesthesia & Analgesia 136(2):p 295-307, February 2023 BACKGROUND: Despite the growing contributions of critical care anesthesiologists to clinical practice, research, and administrative leadership of intensive care units (ICUs), relatively little is known about the subspecialty-specific clinical practice environment. An understanding of contemporary clinical practice is essential to recognize […]

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Uncategorized Published - 14 February, 2023    By - Dr Clemens
Complications and Technical Consideration of Ultrasound-Guided Rectus Sheath Blocks: A Retrospective Analysis of 4033 Patients

AUTHORS: Kwon, Hyun-Jung MD et al  Anesthesia & Analgesia 136(2):p 365-372, February 2023 BACKGROUND: Although the ultrasound-guided rectus sheath block (RSB) is usually regarded as an easy and safe procedure in clinical settings, there is currently no report on complications incidence. Therefore, the present study investigated complications in a large cohort and described the technical considerations […]

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Uncategorized Published - 14 February, 2023    By - Dr Clemens
Effects of Goal-Directed Hemodynamic Therapy Using a Noninvasive Finger-Cuff Monitoring Device on Intraoperative Cerebral Oxygenation and Early Delayed Neurocognitive Recovery in Patients Undergoing Beach Chair Position Shoulder Surgery

AUTHORS: Lee, Chen-Tse MD et al  Anesthesia & Analgesia 136(2):p 355-364, February 2023. BACKGROUND: Perioperative cerebral desaturation events (CDEs) and delayed neurocognitive recovery are common among patients undergoing beach chair position (BCP) shoulder surgery and may be caused by cerebral hypoperfusion. This study tested the hypothesis that the application of goal-directed hemodynamic therapy (GDHT) would attenuate […]

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Uncategorized Published - 14 February, 2023    By - Dr Clemens
Perioperative Considerations for Patients with Mpox (Monkeypox)

Authors: Jonathan M. Tan, MD, MPH, MBI, FASA et al Anesthesia Patient Safety Foundation Volume 38, No. 1 • February 2023  INTRODUCTION Mpox, previously known as Monkeypox, is a global health concern.1 While first detected in humans in 1970 in the Republic of the Congo, its spread to nonendemic countries in 2022 led the World Health Organization […]

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Uncategorized Published - 14 February, 2023    By - Dr Clemens
OCP002, a Mixed Agonist of Opioid and Cannabinoid Receptors, Produces Potent Antinociception With Minimized Side Effects

AUTHORS: Xu, Biao PhD et al Anesthesia & Analgesia 136(2):p 373-386, February 2023 BACKGROUND: Increasing attention has been attracted to the development of bifunctional compounds to minimize the side effects of opioid analgesics. Pharmacological studies have verified the functional interaction between opioid and cannabinoid systems in pain management, suggesting that coactivation of the opioid and cannabinoid […]

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Uncategorized Published - 13 February, 2023    By - Dr Clemens
Always Assess the Raw Electroencephalogram: Why Automated Burst Suppression Detection May Not Detect All Episodes

AUTHORS: Fleischmann, Antonia MD et al  Anesthesia & Analgesia 136(2):p 346-354, February 2023. BACKGROUND: Electroencephalogram (EEG)-based monitors of anesthesia are used to assess patients’ level of sedation and hypnosis as well as to detect burst suppression during surgery. One of these monitors, the Entropy module, uses an algorithm to calculate the burst suppression ratio (BSR) that […]

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Uncategorized Published - 13 February, 2023    By - Dr Clemens
Reducing Volatile Anesthetic Waste Using a Commercial Electronic Health Record Clinical Decision Support Tool to Lower Fresh Gas Flows

AUTHORS: Olmos, Andrea V. MD et al Anesthesia & Analgesia 136(2):p 327-337, February 2023. BACKGROUND: Volatile anesthetic consumption can be reduced by minimizing excessive fresh gas flows (FGFs). Currently, it is unknown whether decision support tools embedded within commercial electronic health record systems can be successfully adopted to achieve long-term reductions in FGF rates. The authors […]

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Uncategorized Published - 13 February, 2023    By - Dr Clemens
Health Care Burden Associated With Adolescent Prolonged Opioid Use After Surgery

AUTHORS: Cummings Joyner, Alice Kate MS*; King, Michael R. MD†; Safranek, Conrad BS‡; Parvathinathan, Gomathy MS§; De Souza, Elizabeth PhD§; Anderson, T. Anthony PhD, MD§ Anesthesia & Analgesia 136(2):p 317-326, February 2023. BACKGROUND: Prolonged opioid use after surgery (POUS), defined as the filling of at least 1 opioid prescription filled between 90 and 180 days […]

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