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AUTHORS: Lyu, Wenyuan MD et al Anesthesia & Analgesia 136(1):p 94-100, January 2023. BACKGROUND: Norepinephrine is effective in preventing spinal hypotension during cesarean birth; however, an optimal regimen has not been determined. We hypothesized that an initial bolus of norepinephrine improves efficacy of spinal hypotension prophylaxis beyond continuous norepinephrine alone. METHODS: In this double-blind, controlled study, […]
Read MoreAUTHORS: Lee, Linden O. MD et al Anesthesia & Analgesia 136(1):p 86-93, January 2023. BACKGROUND: Previous studies have suggested that administration of epidural 3% 2-chloroprocaine (CP) before epidural morphine results in decreased analgesic efficacy of epidural morphine. We sought to determine whether these observations were a result of antagonism or a window period between the conclusion […]
Read MoreAUTHORS: Qi, Xin MD et al Anesthesia & Analgesia 136(1):p 79-85, January 2023. BACKGROUND: The aim of this study was to explore whether ice slush (IS) causing local hypothermia can effectively inhibit the oculocardiac reflex (OCR) during strabismus surgery. METHODS: This prospective, randomized, double-blind study included 58 patients with concomitant strabismus scheduled for lateral rectus (LR) […]
Read MoreAUTHORS: Zon, Rebecca L. MD et al Anesthesia & Analgesia 136(1):p 70-78, January 2023. BACKGROUND: Patients with coronavirus disease 2019 (COVID-19) can present with severe respiratory distress requiring intensive care unit (ICU)–level care. Such care often requires placement of an arterial line for monitoring of pulmonary disease progression, hemodynamics, and laboratory tests. During the first wave […]
Read MoreAUTHORS: Jiang, Jia-Li MD et al Anesthesia & Analgesia 136(1):p 60-69, January 2023. BACKGROUND: The effect of anesthesia regimens on postoperative delirium after on-pump cardiac valve surgery is yet undetermined. This study aimed to evaluate the effect of volatile anesthesia compared with propofol-based total intravenous anesthesia (TIVA) on the occurrence of delirium after on-pump cardiac valve […]
Read MoreAUTHORS: O’Gara, Brian P. MD, MPH et al Anesthesia & Analgesia 136(1):p 51-59, January 2023. BACKGROUND: Volatile anesthetics have been historically preferred for cardiac anesthesia, but the evidence for their superiority to intravenous agents is mixed. We conducted a survey to better understand the current state of practice and the rationale behind provider preferences for anesthesia […]
Read MoreAUTHORS: Zhang, Yu MD et al Anesthesia & Analgesia 136(1):p 34-42, January 2023. BACKGROUND: Surgery is accompanied by a systemic inflammatory response that may presage delirium in susceptible individuals. Little is known about the trajectory of plasma proinflammatory cytokines and their potential associations with postoperative delirium (POD). The current study longitudinally assessed both pro and anti-inflammatory […]
Read MoreAUTHORS: Karam, Cynthia MD et al Anesthesia & Analgesia 136(1):p 25-33, January 2023. | BACKGROUND: The removal of the laryngeal mask airway (LMA®) in children may be associated with respiratory adverse events. The rate of occurrence of these adverse events may be influenced by the type of anesthesia. Studies comparing total intravenous anesthesia (TIVA) with propofol and […]
Read MoreAUTHORS: Yao, Yusheng et al European Journal of Anaesthesiology 39(12):p 911-917, December 2022. BACKGROUND Remimazolam is an ultrashort-acting benzodiazepine that is potentially a practical option for procedural sedation in colonoscopy. OBJECTIVE To test the hypothesis that remimazolam could provide a noninferior discharge time to propofol for ambulatory colonoscopy. DESIGN A prospective, randomised, double-blind, noninferiority clinical trial. […]
Read MoreAUTHORS: Gavilan, Eva MSN et al Anesthesia & Analgesia 136(1):p 43-50, January 2023. Abstract The aim of this study was to evaluate the efficacy of presurgical interventions for promoting smoking cessation in terms of achieving smoking abstinence and reducing surgical complication rates. A systematic review of randomized clinical trials (RCTs) published from March 2009 to April […]
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