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AUTHORS: Ruetzler, Kurt MD, PhD, FAHA et al Anesthesia & Analgesia 136(4):p 761-771, April 2023. BACKGROUND: Nociception is the physiological response to nociceptive stimuli, normally experienced as pain. During general anesthesia, patients experience and respond to nociceptive stimuli by increasing blood pressure and heart rate if not controlled by preemptive analgesia. The PMD-200 system from Medasense […]
Read MoreToday is the 247th commemoration of the day the Declaration of Independence was adopted by the Second Continental Congress. Happy Birthday America the Greatest Country Ever
Read MoreDG Journal Club AUTHORS: Sylvain Bise et al Skeletal Radiol. 2023 Feb 2 OBJECTIVE To compare the efficacy of the transforaminal approach (TFA) versus the interlaminar approach (ILA) for CT-guided epidural steroid injection (CTESI) in the treatment of persistent lumbosacral radicular pain (LRP > 6 weeks) with long-term follow-up. METHODS Patients were prospectively assessed for pain by visual […]
Read MoreDG Journal Club AUTHORS: Joseph P Connor et al BMC Cancer. 2023 Jan 28; 23(1): 99 BACKGROUND Both Red Blood Cell (RBC) transfusion and anemia are thought to negatively impact cancer survival. These effects have been reported with mixed findings in cancer of the esophagus. The potential impact of the application of restrictive transfusion strategies […]
Read MoreAUTHORS: Son, Jongbae MD et al Anesthesia & Analgesia 136(4):p 719-727, April 2023. BACKGROUND: Pulmonary resection surgery causes severe postoperative pain and usually requires opioid-based analgesia, particularly in the early postoperative period. However, the administration of large amounts of opioids is associated with various adverse events. We hypothesized that patients who underwent pulmonary resection under an […]
Read MoreAUTHORS: Hsieh, Ming-Chun PhD et al Anesthesia & Analgesia February 08, 2023. BACKGROUND: The microtubule-stabilizing drug paclitaxel (PTX) is an important chemotherapeutic agent for cancer treatment and causes peripheral neuropathy as a common side effect that substantially impacts the functional status and quality of life of patients. The mechanistic role for NIMA-related kinase 2 (NEK2) […]
Read MoreAUTHORS: Zhang, Mingyue MD et al Anesthesia & Analgesia February 08, 2023. BACKGROUND: General anesthetics (eg, propofol and volatile anesthetics) enhance the slow-delta oscillations of the cortical electroencephalogram (EEG), which partly results from the enhancement of (γ-aminobutyric acid [GABA]) γ-aminobutyric acid-ergic (GABAergic) transmission. There is a GABAergic excitatory-inhibitory shift during postnatal development. Whether general anesthetics […]
Read MoreAuthor: Shahla Siddiqui, MD, MS, FCCM et al ASA Monitor July 2023, Vol. 87, 30. Although the use of positive end expiratory pressure (PEEP) for pulmonary edema was described by Barach in 1938, PEEP did not enter routine clinical practice until the late 1960s, when it was used by Gregory and colleagues in neonates with respiratory […]
Read MoreAuthor: Jenna Fletcher MedicalNewsToday February 1, 2023 There are several ways a person can help manage sciatic nerve pain at night, including adjusting sleep positions and trying pain relief remedies before bed. Sciatic nerve pain typically starts in the lower back or buttocks and radiates to the back of the thigh and legs or feet. […]
Read MoreDG Journal Club AUTHORS: Thibaut Vanneste et al Reg Anesth Pain Med. 2023 Jan 18 BACKGROUND Radiofrequency (RF) treatment of the genicular nerves has the potential to reduce chronic knee pain due to osteoarthritis or persistent postsurgical pain, however, a direct comparison between the two main modalities METHODS This double blind, non-inferiority, pilot, randomized controlled […]
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