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Uncategorized Published - 7 August, 2023    By - Dr Clemens
Selective Activation of NAc D1R-VP/LH Circuits Promotes Reanimation From Sevoflurane Anesthesia in Mice

AUTHORS: Bao, Weiwei PhD et al  Anesthesia & Analgesia 137(1):p 87-97, July 2023. BACKGROUND: Emerging evidence has uncovered a vital role of nucleus accumbens (NAc) neurons that express the dopamine D1 receptor (D1R) and its upstream neural circuit in general anesthesia (GA) regulation. However, the underlying downstream neural basis of the modulation of GA emergence by […]

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Uncategorized Published - 4 August, 2023    By - Dr Clemens
FDA announces recall of nearly 8,000 Impella blood pumps due to risk of injury or death in TAVR patients

Author: Michael Walter  Cardiovascular Business The U.S. Food and Drug Administration (FDA) has announced that Abiomed is recalling all of its left-sided Impella blood pumps. This is a Class I recall, which means using these devices “may cause serious injuries or death.” However, the devices do not need to be returned; the recall is in place to […]

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Uncategorized Published - 4 August, 2023    By - Dr Clemens
Ultrasound Assessment of Gastric Fluid Volume in Children Scheduled for Elective Surgery After Clear Fluid Fasting for 1 Versus 2 Hours

AUTHORS: Sarhan, Khaled Abdelfattah MD, DESA et al Anesthesia & Analgesia 136(4):p 711-718, April 2023. BACKGROUND: This study aimed to compare the gastric fluid volume (GFV) in children who fasted 1 versus 2 hours using ultrasound, after ingestion of a defined volume of clear fluid. METHODS: Children scheduled for elective surgery were enrolled in this randomized, […]

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Uncategorized Published - 4 August, 2023    By - Dr Clemens
What is the connection between COVID-19 and shingles?

This is for our readers who treat chronic pain patients. Author: Adam Rowden MedicalNewsToday COVID-19 and shingles are both viral infections. Though COVID-19 does not cause shingles, there may be a link between the two conditions. COVID-19 is a highly infectious disease that a person can develop if they acquire the SARS-CoV-2 virus. Evidence suggests that people […]

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Uncategorized Published - 4 August, 2023    By - Dr Clemens
Associations Between Systemic and Cerebral Inflammation in an Ovine Model of Cardiopulmonary Bypass

AUTHORS: Elsaafien, Khalid PhD et al Anesthesia & Analgesia 136(4):p 802-813, April 2023. BACKGROUND: Intraoperative inflammation may contribute to postoperative neurocognitive disorders after cardiac surgery requiring cardiopulmonary bypass (CPB). However, the relative contributions of general anesthesia (GA), surgical site injury, and CPB are unclear. METHODS: In adult female sheep, we investigated (1) the temporal profile of proinflammatory […]

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Uncategorized Published - 4 August, 2023    By - Dr Clemens
Role of Tumor Necrosis Factor Receptor 1—Reactive Oxygen Species—Caspase 11 Pathway in Neuropathic Pain Mediated by HIV gp120 With Morphine in Rats

AUTHORS: Hayashi, Kentaro MD et al  Anesthesia & Analgesia 136(4):p 789-801, April 2023. BACKGROUND: Recent clinical research suggests that repeated use of opioid pain medications can increase neuropathic pain in people living with human immunodeficiency virus (HIV; PLWH). Therefore, it is significant to elucidate the exact mechanisms of HIV-related chronic pain. HIV infection and chronic morphine […]

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Uncategorized Published - 3 August, 2023    By - Dr Clemens
Validation of Automated Data Extraction From the Electronic Medical Record to Provide a Pediatric Risk Assessment Score

AUTHORS: Valencia, Eleonore MD et al  Anesthesia & Analgesia 136(4):p 738-744, April 2023. BACKGROUND: Although the rate of pediatric postoperative mortality is low, the development and validation of perioperative risk assessment models have allowed for the stratification of those at highest risk, including the Pediatric Risk Assessment (PRAm) score. The clinical application of such tools requires […]

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Uncategorized Published - 3 August, 2023    By - Dr Clemens
Undergraduate Anesthesia Skills for a Global Surgery Agenda: Students’ Self-Reported Competence

AUTHORS: Spijkerman, Sandra FCA(SA) et al  Anesthesia & Analgesia March 08, 2023.  BACKGROUND: Safe anesthesia is imperative for the Global Surgery agenda and Sustainable Development Goal 3. Due to a shortage of specialists in South Africa (SA), anesthetic services are often provided by nonspecialist doctors, often newly qualified and frequently without immediate supervision. The burden […]

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Uncategorized Published - 3 August, 2023    By - Dr Clemens
Ketamine Induces Delirium-Like Behavior and Interferes With Endosomal Tau Trafficking

AUTHORS: Ren, Xinghua MD, PhD et al  Anesthesia & Analgesia 136(4):p 779-788, April 2023. BACKGROUND: Ketamine is an intravenous anesthetic. However, whether ketamine can induce neurotoxicity and neurobehavioral deficits remains largely unknown. Delirium is a syndrome of acute brain dysfunction associated with anesthesia and surgery in patients, and tau protein may contribute to postoperative delirium. Finally, […]

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Uncategorized Published - 3 August, 2023    By - Dr Clemens
Top 3 anesthesia residency programs in 2023: Doximity

Author: Riz Hatton  Becker’s ASC Review Here are the top three residency programs for anesthesiology, according to Doxmity’s Residency Navigator. Note: Rankings are accurate as of July 25, 2023. 1. Massachusetts General Hospital (Boston) Program size: 116 2. University of California (San Francisco) Program size: 96 3. Brigham and Women’s Hospital (Boston) Program size: 128

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