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MedicalNewsToday Improving outcomes for people with heart conditions was a recurring theme this week. We reported on how treatment with the “hunger hormone” ghrelin boosts pumping capacity after heart failure, and on the importance of more frequent follow-up phone calls after leaving hospital for people with heart failure. But perhaps most intriguing of all is a recent discovery that […]
Read MoreAUTHORS: Wong, Stanley Sau Ching MD et al Anesthesia & Analgesia 137(1):p 59-71, July 2023. BACKGROUND: Buprenorphine is a partial agonist at the µ-opioid receptor and an antagonist at the delta and kappa opioid receptors. It has high affinity and low intrinsic activity at the µ-opioid receptor. Buprenorphine demonstrates no ceiling effect for clinical analgesia, but […]
Read MoreAUTHORS: Capdevila, Xavier MD, PhD et al Anesthesia & Analgesia 137(2):p 322-331, August 2023. BACKGROUND: The management of perioperative iron deficiency is a component of the concept of patient blood management. The objective of this study was to update French data on the prevalence of iron deficiency in patients scheduled for major surgery. METHODS: The CARENFER […]
Read MoreAUTHORS: Fehrlin, Eloy S. MD et al Anesthesia & Analgesia March 24, 2023. BACKGROUND: Other than clinical observation of a patient’s vegetative response to nociception, monitoring the hypnotic component of general anesthesia (GA) and unconsciousness relies on electroencephalography (EEG)-based indices. These indices exclusively based on frontal EEG activity neglect an important observation. One of the […]
Read MoreAUTHORS: Zhao, Xingkai MS et al Anesthesia & Analgesia 136(6):p 1206-1216, June 2023. BACKGROUND: The anesthetic isoflurane can cause neurotoxicity in fetuses and offspring of rats, affecting their neurodevelopment. However, the underlying mechanisms and therapeutic targets of isoflurane-induced neurotoxicity remain to be identified. Alfaxalone (ALF) is a steroid anesthetic. Steroids have been reported to have neuroprotective […]
Read MoreAUTHORS: Nasr, Viviane G. MD, MPH, FASA et al Anesthesia & Analgesia 137(2):p 313-321, August 2023. Abstract Pediatric cardiac anesthesiology has developed as a subsubspecialty of anesthesiology over the past 70 years. The evolution of this specialty has led to the establishment in 2005 of a dedicated professional society, the Congenital Cardiac Anesthesia Society (CCAS). By […]
Read MoreAUTHORS: Zanolli, Nicole C. BA et al Anesthesia & Analgesia 137(2):p 256-266, August 2023. BACKGROUND: Optimizing analgesia after cesarean delivery is essential to quality of patient recovery. The American Society of Anesthesiologists and the Society for Obstetric Anesthesia and Perinatology recommend multimodal analgesia (MMA). However, little is known about clinical implementation of these guidelines after cesarean […]
Read MoreAuthor: Karen Veazey MedicalNewsToday Epidural steroid injections can deliver an anti-inflammatory steroid into the epidural space around the spinal cord. It is unclear why this might cause a temporary increase in pain before bringing relief, but it may involve the irritation of nerve roots extending from the spine. Epidural steroid injections can offer improvements to […]
Read MoreAUTHORS: Dalia, Adam A. MD, MBA, FASE et al Anesthesia & Analgesia 137(2):p 293-302, August 2023. Increasing cardiac procedural volume, a shortage of practicing cardiac anesthesiologists, and growth in specialist physician compensation would be expected to increase cardiac anesthesiologist compensation and work load. Additionally, more cardiac anesthesiologists are graduating from accredited fellowships and completing echocardiography certification. […]
Read MoreAUTHORS: Illescas, Alex MPH et al Anesthesia & Analgesia 136(6):p 1182-1188, June 2023. BACKGROUND: Surgical patients with preexisting neurological diseases create greater challenges to perioperative management, and choice of anesthetic is often complicated. We investigated neuraxial anesthesia use in total knee and hip arthroplasty (TKA/THA) recipients with multiple sclerosis or myasthenia gravis compared to the general […]
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