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Uncategorized Published - 31 August, 2023    By - Dr Clemens
Methadone Clinics and Long-Term Efficacy for Opioid Use Disorder

Authors: Daguio K, Hwang R, Oladinni D, Keane JF, Goldstein LB. Practical Pain Manage. 2023 July August 23(4). A review and perspective on the adverse effects of methadone maintenance treatment, including emerging alternatives to treating OUD. Introduction Methadone is a mu opioid agonist that binds to receptors located in the central nervous system (CNS) and […]

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Uncategorized Published - 30 August, 2023    By - Dr Clemens
Sedatives and Postoperative Delirium: Reply

Authors: Hyun-Jung Shin, M.D., Ph.D.; Hyo-Seok Na, M.D., Ph.D. Anesthesiology August 2023. In Reply: We thank Nelson et al.,  Goodwin et al., and Hughes et al.  for their responses to our article. We would like to express our gratitude to Nelson et al.  for raising important concerns. The fragility index is a novel method for measuring the robustness of results in randomized […]

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Uncategorized Published - 30 August, 2023    By - Dr Clemens
Sedatives and Postoperative Delirium: Comment

Authors: Lauren M. Hughes, M.D. et al  Anesthesiology August 2023. To the Editor We read with great interest the recent article by Shin et al. which concluded that dexmedetomidine shows a lower incidence of postoperative delirium compared to propofol sedation in healthy older adults undergoing lower limb surgery during spinal anesthesia, which included patients aged greater than […]

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Uncategorized Published - 30 August, 2023    By - Dr Clemens
Sedatives and Postoperative Delirium: Comment

Authors: Mark Nelson, M.D., M.Ed. et al  Anesthesiology August 2023. To the Editor: We read with interest the randomized controlled trial in the journal by Shin et al.  comparing postoperative delirium rates in patients undergoing major joint replacement surgery under spinal anesthesia using propofol versus dexmedetomidine sedation. Not only does this trial inform on which agent may result in […]

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Uncategorized Published - 30 August, 2023    By - Dr Clemens
Sedatives and Postoperative Delirium: Comment

Authors: Brandon Goodwin, B.A. et al  Anesthesiology August 2023. To the Editor: We read with great interest, “Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial” by Shin et al.  It reported that the incidence of delirium was less in the group receiving propofol versus dexmedetomidine. The […]

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Uncategorized Published - 30 August, 2023    By - Dr Clemens
Pulsed Electro-magnetic Field Therapy for Musculoskeletal Pain

Authors: TMarovino T, Tassone E. Practical Pain Manag. 2023 July/August;23(4). Science of PEMF Pulsed electro-magnetic field (PEMF) science has evolved over the years, and dedicated research on this topic, specifically as it applies to pain management, has been growing. Independent research on PEMF has consistently demonstrated meaningful physiological treatment effects in three areas: pain, inflammation, […]

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Uncategorized Published - 29 August, 2023    By - Dr Clemens
Association of labor neuraxial analgesia with maternal blood transfusion

Authors: Jean Guglielminotti, MD, PhD et al  Anesthesiology August 2023. Background Labor neuraxial analgesia may reduce the odds of postpartum hemorrhage, the leading indication for maternal blood transfusion during childbirth. This study tested the hypothesis that labor neuraxial analgesia is associated with reduced odds of maternal blood transfusion overall. Methods US birth certificate data in […]

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Uncategorized Published - 29 August, 2023    By - Dr Clemens
Bicarbonate: From Physiology to Clinical Practice: Reply

Authors: Silvia Coppola, M.D. et al  Anesthesiology August 2023. To the Editor: We would like to thank Hess and Long for their comments on our article who emphasized the role of acidemia-associated coagulopathy in terms of decreasing fibrinogen concentration, reducing coagulation factors and promoting a state of hypocoagulability. Furthermore, the correction of the state of […]

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Uncategorized Published - 29 August, 2023    By - Dr Clemens
Bicarbonate: From Physiology to Clinical Practice: Comment

Authors: Aaron S. Hess, M.D., Ph.D.; Micah T. Long, M.D. Anesthesiology August 2023. To the Editor: We deeply appreciated Dr. Coppola et al.’s thorough yet concise review of acid-base physiology and the clinical indications for sodium bicarbonate.  One more complication of acidosis deserves mention: coagulopathy. Although acidosis is often a secondary effect of injury and […]

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Uncategorized Published - 29 August, 2023    By - Dr Clemens
Bridging the Gap With Your Mobile Phone

Authors: Saeedah Asaf, MBBS; M. Saif Siddiqui, MBBS ASA Monitor August 2023, Vol. 87, 22–23. The mobile phone revolution has resulted in more people with access to cell phones than clean water and electricity. Now, 104 per 100 people have access to mobile phones in developing countries (Figure) (asamonitor.pub/462PUVd). In collaboration with tech companies, global health organizations […]

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