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Authors: George Tewfik, MD, MBA, FASA, CPE, MSBA et al ASA Monitor October 2023, Vol. 87, e2–e3. Picture two starkly different scenarios… In Hospital A, the regional anesthesia team mandates and directs the perioperative analgesic plan. When the acute pain attending for the day and the resident identify a patient on the OR schedule who may […]
Read MoreASA Monitor October 2023, Vol. 87, 1–5. A 3-year-old male presented for an elective circumcision. He was an ex-32-week preemie with reactive airways and a recent URI requiring nebulized albuterol. The URI resolved 3 weeks ago, and he took a course of antibiotics. PO midazolam was given in pre-op holding area for anxiolysis, and he was […]
Read MoreASA Monitor October 2023, Vol. 87, 7. Which of the following train-of-four (TOF) patterns shown on the right is MOST consistent with partial recovery from a phase II block following neuromuscular blockade using a succinylcholine infusion? Succinylcholine is among the oldest anesthesia medications still in common use. An intubating dose of succinylcholine produces complete neuromuscular blockade […]
Read MoreASA Monitor October 2023, Vol. 87, 12–13. A new study funded by the National Heart, Blood, and Lung Institute (NHLBI) provides strong evidence for omega-3 fatty acids’ power to maintain lung health. Researchers interested in nutritional interventions that could prevent lung disease have long suspected that omega-3s could aid lung disease prevention due to their anti-inflammatory […]
Read MoreAuthors: Mark A. Shulman, Ph.D. et al Anesthesiology October 2023, Vol. 139, 420–431. Background Older patients are vulnerable to developing new or worsening disability after surgery. Despite this, patient or surgical characteristics predisposing to postoperative disability are poorly defined. The aim of the study was to develop and validate a model, subsequently transformed to point-score form, […]
Read MoreAuthors: Haobo Ma, MD, MSc et al Anesthesiology September 2023. Background The treatment of intraoperative hypotension with phenylephrine may impair cerebral perfusion through vasoconstriction, which has been linked to postoperative delirium. We hypothesized that intraoperative administration of phenylephrine, compared to ephedrine, is associated with higher odds of postoperative delirium. Methods 103,094 hospitalized adults undergoing general […]
Read MoreAuthors: Pavel S. Roshanov et al Anesthesiology September 2023. Background In prior analyses, myocardial injury after noncardiac surgery, major bleeding, and sepsis were independently associated with most deaths in the 30 days after noncardiac surgery, but most of these deaths occurred during the index hospitalization for surgery. We set out to describe outcomes after discharge […]
Read MoreAuthors: Jacqueline M. Leung, M.D., M.P.H. et al Anesthesiology October 2023, Vol. 139, 432–443. Background The pathophysiology of delirium is incompletely understood, including what molecular pathways are involved in brain vulnerability to delirium. This study examined whether preoperative plasma neurodegeneration markers were elevated in patients who subsequently developed postoperative delirium through a retrospective case-control study. Methods […]
Read MoreAuthors: Edita Navratilova, Ph.D. et al Anesthesiology September 2023. Background The efficiency of descending pain modulation, commonly assessed with the conditioned pain modulation (CPM) procedure, is diminished in patients with chronic pain. We hypothesized that the efficiency of pain modulation is controlled by cortical opioid circuits. Methods We evaluated the effects of mu opioid receptor […]
Read MoreAuthor: Wael Saasouh, MD IARS Newsletter Issue 4 Intraoperative hypotension has been shown to negatively influence patient outcomes based on large trials from major academic centers. During the session, “A Pragmatic Discussion on Intraoperative Hypotension” on Saturday, April 15 at the IARS 2023 Annual Meeting, experts on this topic shared the results of similar work […]
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