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Authors: Lauren M. Hughes, M.D. et al Anesthesiology November 2023, Vol. 139, 709. To the Editor: We read with great interest the recent article by Shin et al. which concluded that dexmedetomidine shows a lower incidence of postoperative delirium compared to propofol sedation in healthy older adults undergoing lower limb surgery during spinal anesthesia, which included patients […]
Read MoreAuthors: Mark Nelson, M.D., M.Ed. et al Anesthesiology November 2023, Vol. 139, 708. To the Editor: We read with interest the randomized controlled trial in the journal by Shin et al. comparing postoperative delirium rates in patients undergoing major joint replacement surgery under spinal anesthesia using propofol versus dexmedetomidine sedation. Not only does this trial inform on which agent may […]
Read MoreAuthors: Benjamin Steinhorn, M.D., Ph.D. et al Anesthesiology November 2023, Vol. 139, 705–707. To the Editor: Since their introduction more than a decade ago, sodium glucose transporter 2 inhibiting drugs have established themselves as important tools in the management of diabetes, chronic kidney disease, and heart failure. However, periprocedural euglycemic diabetic ketoacidosis has been associated with […]
Read MoreAuthors: Jan Ngian, M.B.B.S. et al Anesthesiology November 2023, Vol. 139, 665–666. These images belong to a 30-yr-old man who underwent an arthroscopic knee meniscal repair. He had a body mass index of 29 kg/m2 and endorsed occasional mild gastroesophageal reflux after spicy food. Induction of anesthesia was unremarkable. A laryngeal mask airway (LMA) was inserted with a […]
Read MoreAuthors: Aurora Magliocca, M.D., Ph.D. et al Anesthesiology November 2023, Vol. 139, 628–645. Background The catabolism of the essential amino acid tryptophan to kynurenine is emerging as a potential key pathway involved in post–cardiac arrest brain injury. The aim of this study was to evaluate the effects of the modulation of kynurenine pathway on cardiac arrest […]
Read MoreAuthors: Nickil R Agni et al Lancet 2023 Jul 15;402(10397):196-202. Background: Hip fracture is the most common injury requiring treatment in hospital. Controversy exists regarding the use of antibiotic loaded bone cement in hip fractures treated with hemiarthroplasty. We aimed to compare the rate of deep surgical site infection in patients receiving high-dose dual-antibiotic loaded […]
Read MoreAuthors: Jacob N Schroder et al N Engl J Med 2023 Jun 8;388(23):2121-2131 Background: Data showing the efficacy and safety of the transplantation of hearts obtained from donors after circulatory death as compared with hearts obtained from donors after brain death are limited. Methods: We conducted a randomized, noninferiority trial in which adult candidates for heart transplantation […]
Read MoreAuthors: Peter L. Kovacs, M.D. et al Anesthesiology November 2023, Vol. 139, 664. The figure is from the preanesthetic airway assessment of a 56-yr-old man scheduled for laparoscopic hernia repair. His epiglottis was visible on tongue protrusion (unusual “Mallampati Zero” classification) and was adhered to the uvula as well. The patient related an uneventful past surgical history, although […]
Read MoreAuthors: Russell L Gruen et al N Engl J Med 2023 Jul 13;389(2):127-136 Background: Whether prehospital administration of tranexamic acid increases the likelihood of survival with a favorable functional outcome among patients with major trauma and suspected trauma-induced coagulopathy who are being treated in advanced trauma systems is uncertain. Methods: We randomly assigned adults with major […]
Read MoreAuthors: Matthias Heringlake, M.D. et al Anesthesiology November 2023, Vol. 139, 701–704. To the Editor: Transfemoral transcatheter aortic valve replacement has become the standard of care for older patients with symptomatic aortic stenosis. While most procedures were initially performed under general anesthesia, based on the assumption that avoiding general anesthesia may improve postinterventional well-being and patient satisfaction, […]
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