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Authors: Michael F. Aziz, MD et al Anesthesiology October 2023. Background: Surgical procedures performed on patients with recent exposure to COVID-19 infection have been associated with increased mortality risk in prior studies. Accordingly, elective surgery is often delayed after infection. We aimed to compare 30-day hospital mortality and postoperative complications (acute kidney injury, pulmonary complications) […]
Read MoreAuthor: Don Goldeberg MD Pract Pain Manag. 2023 March/April;22(2). Test your clinical knowledge with five case examples on how to make a differential diagnosis for acute widespread pain. An abrupt onset of widespread musculoskeletal pain is commonly seen in primary care and specialty medicine. There are multiple potential causes for such pain, including brief self-limited […]
Read MoreAUTHORS: Azizi, Paymon M. MSc et al Anesthesia & Analgesia 137(3):p 629-637, September 2023. BACKGROUND: Acute myocardial injury after noncardiac surgery, which is most often symptomatically silent, is associated with increased mortality and morbidity. However, it is not known if routine postoperative troponin testing will affect patient outcomes. METHODS: We assembled a cohort of patients who […]
Read MoreAuthor: Mariah Taylor Becker’s Hospital Review A Chicago-based Northwestern Medicine researcher found acupuncture can improve patient outcomes following cardiac surgery. In a study conducted by the health system, a small group of patients were treated with daily acupuncture following open heart surgery. The treatment was delivered in the patient’s hospital room by three licensed acupuncturists, who coordinated […]
Read MoreAuthors: Anjali A. Dixit, M.D., M.P.H. et al Anesthesiology November 2023, Vol. 139, 580–590. Background Insured patients who receive out-of-network care may receive a “balance bill” for the difference between the practitioner’s charge and their insurer’s contracted rate. In 2017, California banned balance billing for anesthesia care. This study examined the association between California’s law and […]
Read MoreAUTHORS: Atandi, Bryan Ogoti MD et al Anesthesia & Analgesia 137(3):p 648-655, September 2023. BACKGROUND: Anesthetic monitoring within standards defined by various professional anesthesia organizations has been shown to reduce perioperative mortality. Given the scarce resources for anesthesia and surgery in low- to middle-income countries, we sought to determine the availability of recommended monitoring devices in […]
Read MoreAuthors: Phillip E. Vlisides, M.D. et al Anesthesiology November 2023, Vol. 139, 568–579. Background Perioperative neurocognitive disorders are a major public health issue, although there are no validated neurophysiologic biomarkers that predict cognitive function after surgery. This study tested the hypothesis that preoperative posterior electroencephalographic alpha power, alpha frontal-parietal connectivity, and cerebral oximetry would each correlate […]
Read MoreAUTHORS: Schnetz, Michael P. MD, PhD et al Anesthesia & Analgesia August 15, 2023. BACKGROUND: Although patients are commonly monitored for depth of anesthesia, it is unclear to what extent administration of intravenous anesthetic medications may affect calculated bispectral (BIS) index values under general anesthesia. METHODS: In a retrospective analysis of electronic anesthesia records from […]
Read MoreAUTHORS: Arias, Hugo R. PhD et al Anesthesia & Analgesia 137(3):p 691-701, September 2023. BACKGROUND: The primary objective of this study was to characterize the pharmacological and behavioral activity of 2 novel compounds, DM497 [(E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide] and DM490 [(E)-3-(furan-2-yl)-N-methyl-N-(p-tolyl)acrylamide], structural derivatives of PAM-2, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR). METHODS: A mouse […]
Read MoreAUTHORS: Moiseiwitsch, Nina BS et al Anesthesia & Analgesia 137(3):p 682-690, September 2023. BACKGROUND: Bleeding is a serious complication of cardiopulmonary bypass (CPB) in neonates. Blood product transfusions are often needed to adequately restore hemostasis, but are associated with significant risks. Thus, neonates would benefit from other effective, and safe, hemostatic therapies. The use of fibrinogen […]
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