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Uncategorized Published - 20 December, 2023    By - Dr Clemens
Rapid Titration of Intravenous Treprostinil to Treat Severe Pulmonary Arterial Hypertension Postpartum

AUTHORS: Wang, Tengke MD et al  Anesthesia & Analgesia 129(6):p 1607-1612, December 2019. BACKGROUND: Pulmonary hypertension during pregnancy carries high mortality rate. The relatively long-acting, specific pulmonary vasodilator treprostinil has been used to improve survival in these parturients. Slow uptitration is performed in most cases, and rapid titration has not been reported in the postpartum period. […]

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Uncategorized Published - 20 December, 2023    By - Dr Clemens
An Initial Investigation of Diaphragm Neurostimulation in Patients with Acute Respiratory Distress Syndrome

Authors: Mélodie Parfait, MD et al  Anesthesiology December 2023. Background Lung protective ventilation aims at limiting lung stress and strain. By reducing the amount of pressure transmitted by the ventilator into the lungs, diaphragm neurostimulation offers a promising approach to minimize ventilator induced lung injury. This study investigates the physiological effects of diaphragm neurostimulation in […]

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Uncategorized Published - 20 December, 2023    By - Dr Clemens
Lung Ultrasound Score on Postoperative Day One is predictive of the occurrence of Pulmonary Complications After Major Abdominal Surgery

Authors: Jeremy Boussier, M.D., Ph.D. et al  Anesthesiology December 2023. Background Postoperative pulmonary complications following major abdominal surgery are frequent and carry high morbidity and mortality. Early identification of patients at risk of pulmonary complications by lung ultrasound may allow the implementation of preemptive strategies. We hypothesized that lung ultrasound score would be associated with […]

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Uncategorized Published - 20 December, 2023    By - Dr Clemens
Achieving Age-Friendly Health Care in an Outpatient Perioperative Clinic

Authors: Heather Lander, MD et al  ASA Monitor January 2023, Vol. 87, 20–21. According to a recent World Health Organization (WHO) publication, in 2020 the number of people aged 60 years and older outnumbered children younger than 5 years worldwide (asamonitor.pub/3NC2L83). Simultaneous to the rapidly growing older population, their surgical and perioperative needs are also increasing. […]

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Uncategorized Published - 20 December, 2023    By - Dr Clemens
In vitro model of prepacked carbon dioxide absorber use: development and testing

Authors: Jennifer Jouwena, M.D. et al  Anesthesiology December 2023. Background CO2 absorbers allow the use of fresh gas flows (FGF) below minute ventilation (V̇E). Models are developed and tested in vitro to quantify their performance with variable CO2 load (V̇CO2), FGF, V̇E, end-tidal CO2 fraction (FETCO2), and the type of workstation used. Methods First principles are used to […]

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Uncategorized Published - 19 December, 2023    By - Dr Clemens
Perioperative Management for Complex Spine Fusion Surgery

Authors: Louanne M. Carabini, M.D. et al  Anesthesiology December 2023. The number of complex spine surgeries performed worldwide on an annual basis continues to rise at a remarkable rate, with greater than 400,000 spinal fusions estimated to occur annually throughout the United States.  Some of the purported reasons for this trend include an aging population, […]

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Uncategorized Published - 19 December, 2023    By - Dr Clemens
Perioperative Care for Aging Rural Populations: Barriers to Care and Potential Solutions

Authors: Heather Lander, MD et al  ASA Monitor September 2023, Vol. 87, 21. Projections from the United States census anticipate that one quarter of Americans will be 65 years or older within a decade, effectively doubling to 95 million older adults (asamonitor.pub/3pLIbun). The Administration on Aging finds over 17% of people living in the U.S. are […]

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Uncategorized Published - 19 December, 2023    By - Dr Clemens
Remimazolam dosing for gastroscopy: a randomized noninferiority trial

Authors: Huichen Zhu, M.D. et al  Anesthesiology December 2023. Background Remimazolam, an ultra-short-acting benzodiazepine, may provide adequate sedation for endoscopy while causing less cardiovascular or respiratory disturbance than propofol. Although fixed-dose administration is suggested, body weight affects the volume of the central chamber and thus affects the sedation depth that can be achieved by the […]

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Uncategorized Published - 19 December, 2023    By - Dr Clemens
Perioperative Management for Complex Spine Fusion Surgery

Authors: Louanne M. Carabini, M.D. et al  Anesthesiology December 2023. The number of complex spine surgeries performed worldwide on an annual basis continues to rise at a remarkable rate, with greater than 400,000 spinal fusions estimated to occur annually throughout the United States.  Some of the purported reasons for this trend include an aging population, with […]

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Uncategorized Published - 19 December, 2023    By - Dr Clemens
Acid–Base Analysis in the Operating Room: A Bedside Stewart Approach

Author: David A. Story, M.B.B.S., M.D., B.Med.Sci., Dip.P.O.M., F.A.N.Z.C.A. Anesthesiology December 2023, Vol. 139, 860–867. All models are wrong but some are useful. —George Box, British statistician, 1976 Most patients receiving anesthesia care have some care-driven changes in their acid–base status, at least mild respiratory acidosis during general anesthesia with spontaneous ventilation. However, many high-risk patients […]

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