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Author: Noah Tong Fierce Healthcare A new report finds the Medicare hospital trust fund will be solvent for 12 more years instead of seven. (Getty Images/ Andrii Yalanskyi) The Hospital Insurance Trust Fund will be fully solvent for longer than previously projected, according to an annual Medicare Trustee report. Though the report (PDF) details “significant financing issues,” […]
Read MoreAUTHORS: Hofer, Ryan E. MD et al Anesthesia & Analgesia October 06, 2023. BACKGROUND: Kidney transplant is the most common transplant operation performed in the United States. Although various approaches to pain management have been described, the optimal analgesic strategy remains undefined. Specifically, the role of intrathecal opioids in this patient population has not been […]
Read MoreAUTHORS: Okada, Carol R. MD et al Anesthesia & Analgesia 138(1):p 99-107, January 2024. BACKGROUND: Childhood obesity is a significant problem. Obesity may alter the pharmacokinetics (PKs) of medications. Fentanyl is commonly used for procedural sedation, but there is a paucity of bolus dose fentanyl PK data in obese children. Better understanding of fentanyl PK in […]
Read MoreAUTHORS: L. JOSEPH PARKER, MD KevinMD.com She walked in with a cane, bent over like a question mark. She was in her seventies and as sweet as people in that age group tend to be. I think most of the cranky ones don’t make it that far. She was something of an emergency because her […]
Read MoreAUTHORS: Lohela, Terhi J. MD, PhD et al Anesthesia & Analgesia 138(3):p 598-606, March 2024. BACKGROUND: Subanesthetic ketamine may reduce perioperative consumption of opioids. We studied whether intravenous S-ketamine alters the pharmacokinetics of oral morphine in healthy volunteers. METHODS: In this paired, randomized, double-blind, crossover trial, 12 participants under a 2-hour intravenous S-ketamine (0.57 mg/kg/h) […]
Read MoreAUTHORS: Dexter, Franklin MD, PhD, FASA*; Epstein, Richard H. MD, FASA† Anesthesia & Analgesia 137(5):p 1104-1109, November 2023. BACKGROUND: Sevoflurane and desflurane are halogenated hydrocarbons with global warming potential. We examined the maximum potential benefit assuming 100% efficiency of waste gas capture technology used in operating rooms and recovery locations. METHODS: We performed computer simulations […]
Read MoreAUTHORS: Saengsin, Kwannapas MD et al Anesthesia & Analgesia 137(5):p 1056-1065, November 2023. BACKGROUND: Phosphodiesterase inhibitors are known to relieve symptoms in the setting of heart failure, although their effects in restrictive ventricular physiology have been poorly characterized. We explored the association between the use of milrinone and volume administration during the first 72 hours following […]
Read MoreAUITHORS: Kelava, Marta MD, MS et al Anesthesia & Analgesia 138(5):p 1003-1010, May 2024 BACKGROUND: Arterial hyperoxemia may cause end-organ damage secondary to the increased formation of free oxygen radicals. The clinical evidence on postoperative lung toxicity from arterial hyperoxemia during cardiopulmonary bypass (CPB) is scarce, and the effect of arterial partial pressure of oxygen (Pao2) […]
Read MoreAUTHORS: Sprung, Juraj MD, PhD et al Anesthesia & Analgesia 137(5):p 1066-1074, November 2023. BACKGROUND: Whether volatile anesthetic solubility affects postanesthesia recovery time in clinical practice is unclear. We investigated the association among 3 volatile agents and 2 clinically relevant outcomes—postanesthesia care unit (PACU) recovery time (time from PACU admission to fulfillment of discharge criteria) and […]
Read MoreAuthors: Dibash Kumar Das, PhD; Steven Shafer, MD, FASA ASA Monitor September 2023, Vol. 87, 1–4. Hosting the 95th Academy Awards, Jimmy Kimmel opened his monologue by saying, “Everybody looks so great! When I look around this room, I can’t help but wonder, ‘Is Ozempic right for me?’” Semaglutide (Ozempic, Wegovy, and Rybelsus) is blowing up social media […]
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