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Authors: Aurora N. Quaye, M.D. et al Anesthesiology June 2024, Vol. 140, 1088–1097. Background Colorectal cancer is a leading cause of cancer-related death. Adenomas and serrated polyps are precursors of colorectal cancer, with serrated polyps being more difficult to detect during colonoscopy. The relationship between propofol use and polyp detection remains unclear. The authors investigated the […]
Read MoreAuthors: Ramón Eizaga Rebollar, M.D. et al Anesthesiology June 2024, Vol. 140, 1203–1204. Figure 1, B and C correspond to a healthy 2-yr-old boy who underwent hypospadias repair during general anesthesia combined with ultrasound-guided continuous caudal block. Mid-sagittal plane lumbar ultrasound (Sonosite SII, FUJIFILM Sonosite, Inc., USA) showed the dural sac end at S4 vertebral level, significantly lower for […]
Read MoreAuthors: Raquel Pereira-Silva, Ph.D. et al Anesthesiology June 2024, Vol. 140, 1176–1191. Background The dorsal reticular nucleus is a pain facilitatory area involved in diffuse noxious inhibitory control (DNIC) through opioidergic mechanisms that are poorly understood. The hypothesis was that signaling of μ-opioid receptors is altered in this area with prolonged chronic inflammatory pain and that […]
Read MoreHonoring the Heroes: A Reflection on Memorial Day I want to thank our readers and wish them a fun and safe Memorial Day. Please remember that today is a day of reflection, remembrance, and gratitude for those who laid down their lives in service to the nation. Memorial Day serves as a powerful reminder of […]
Read MoreAuthors: Mats Enlund, M.D., Ph.D. et al Anesthesiology June 2024, Vol. 140, 1126–1133. Background Prospective interventional trials and retrospective observational analyses provide conflicting evidence regarding the relationship between propofol versus inhaled volatile general anesthesia and long-term survival after cancer surgery. Specifically, bladder cancer surgery lacks prospective clinical trial evidence. Methods Data on bladder cancer surgery performed under general […]
Read MoreAuthors: David R. McIlroy, M.D. et al Anesthesiology June 2024, Vol. 140, 1111–1125. Background Acute kidney injury (AKI) is common after major abdominal surgery. Selection of candidate kidney protective strategies for testing in large trials should be based on robust preliminary evidence. Methods A secondary analysis of the Restrictive versus Liberal Fluid Therapy in Major Abdominal […]
Read MoreAuthors: Pooja Parameshwar, M.D. et al Anesthesiology June 2024, Vol. 140, 1098–1110. Background Neuraxial analgesia provides effective pain relief during labor. However, it is unclear whether neuraxial analgesia prevalence differs across U.S. hospitals. The aim of this study was to assess hospital variation in neuraxial analgesia prevalence in California. Methods A retrospective cross-sectional study analyzed birthing […]
Read MoreAuthors: Simone C. Jansen, M.D. et al Anesthesiology June 2024, Vol. 140, 1076–1087. Background The use of anesthetics may result in depression of the hypoxic ventilatory response. Since there are no receptor-specific antagonists for most anesthetics, there is the need for agnostic respiratory stimulants that increase respiratory drive irrespective of its cause. The authors tested whether […]
Read MoreAuthor: David A. Provenzano, MD ASA Monitor January 2024, Vol. 88, e4–e5. With a mission to advance the science and practice of regional anesthesia and pain medicine to improve patient outcomes, the American Society of Regional Anesthesia and Pain Medicine (ASRA Pain Medicine) is always looking at innovative, new ways to progress what’s possible. From new […]
Read MoreAuthors: Douglas A. Colquhoun, M.B.Ch.B., M.Sc., M.P.H. et al Anesthesiology June 2024, Vol. 140, 1062–1064. “Despite these limitations, this study still calls attention to the importance of preserving access to routine propofol use in patients undergoing screening and surveillance colonoscopy.” In this month’s issue of Anesthesiology, Quaye et al. report findings of their investigation into differences […]
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