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Authors: Alexandre Mansour, M.D., Ph.D. et al Anesthesiology June 2024, Vol. 140, 1153–1164. Background Unfractionated heparin, administered during venoarterial extracorporeal membrane oxygenation to prevent thromboembolic events, largely depends on plasma antithrombin for its antithrombotic effects. Decreased heparin responsiveness seems frequent on extracorporeal membrane oxygenation; however, its association with acquired antithrombin deficiency is poorly understood. The objective […]
Read MoreAUTHORS: Lipszyc, Adam C. MD et al Anesthesia & Analgesia 138(6):p 1174-1186, June 2024. BACKGROUND: A noninvasive and accurate method of determining fluid responsiveness in ventilated patients would help to mitigate unnecessary fluid administration. Although carotid ultrasound has been previously studied for this purpose, several studies have recently been published. We performed an updated systematic review […]
Read MoreAuthors: Rahul Baijal, MD; Priti Dalal, MD; Megha Kanjia, MD Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2 SUMMARY:Perioperative complications are more common in patients with SCD compared to the general population with an increased risk of postoperative acute chest syndrome (ACS), infections, vaso-occlusive pain crises, and 30-day mortality. Children with SCD have […]
Read MoreAuthors: Michael Vandenheuvel, MD et al Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2 DEAR RAPID RESPONSE: Since the 1970s, the pulse oximeter (PO) has enabled noninvasive continuous assessment of arterial blood oxygenation as well as pulse rate. The pulse estimate is derived from the plethysmographic waveform and serves as a proxy for […]
Read MoreAuthors: Raquel Pereira-Silva, Ph.D. et al Anesthesiology June 2024, Vol. 140, 1176–1191. Background The dorsal reticular nucleus is a pain facilitatory area involved in diffuse noxious inhibitory control (DNIC) through opioidergic mechanisms that are poorly understood. The hypothesis was that signaling of μ-opioid receptors is altered in this area with prolonged chronic inflammatory pain and that […]
Read MoreAUTHORS: YaDeau, Jacques T. MD, PhD et al Anesthesia & Analgesia 138(6):p 1163-1172, June 2024. BACKGROUND: Optimal analgesic protocols for total knee arthroplasty (TKA) patients remain controversial. Multimodal analgesia is advocated, often including peripheral nerve blocks and/or periarticular injections (PAIs). If 2 blocks (adductor canal block [ACB] plus infiltration between the popliteal artery and capsule of […]
Read MoreAuthors: Michael R. Mathis, MD et al Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2 In an era of near-complete adoption of electronic health records (EHRs) and coalescence of health data across departments and institutions, a growing recognition of practice variation has emerged. Perioperative care is no exception, with recent studies demonstrating wide […]
Read MoreAuthors: L Niklas Daniel Åke Persson, M.Sc. et al Anesthesiology May 2024. Background Impaired glymphatic clearance of cerebral metabolic products and fluids contribute to traumatic and ischemic brain oedema and neurodegeneration in preclinical models. Glymphatic perivascular cerebrospinal fluid (CSF) flow varies between anesthetics possibly due to changes in vasomotor tone and thereby in the dynamics […]
Read MoreAuthors: Baker, Maxwell B. MSc et al Anesthesia & Analgesia 138(6):p 1154-1158, June 2024. | In the United States, the health care sector is responsible for 10% of the nation’s carbon emissions.1 Anesthesia-related care is responsible for 5% of total health care carbon emissions.2 Within hospitals themselves, as much as 33% of waste is produced by perioperative services.3 Medical […]
Read MoreAuthor: Karolina Brook, MD, FASA, CPPS Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2 SUMMARY:Wiretap laws govern the legality of audio recordings and vary state to state. Here, we summarize the various states’ wiretap laws, the remedies or punishments that can be exacted for violation of a wiretap law, and the applicability of […]
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