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Authors: Donna Ron, MD et al ASA Monitor March 2024, Vol. 88, 1–7. The ANESTHESIOLOGY® annual meeting acts as a conduit for pioneering research, with several abstracts presented in 2023 that shed light on different aspects of perioperative brain health. Four thought-provoking abstracts are synthesized below and in the Figure. These abstracts not only offer novel insights into […]
Read MoreAuthors: Arun T, Karim H R, Singha S K, et al. ( Cureus June 28, 2024 16(6): e63380. Background: In the search for opioid-free anesthesia, notable numbers of drugs, singly or in combinations, have been tested with variable results. However, most of the drugs used are not as strong as opioids. Even if some non-opioid […]
Read MoreAuthor: Martin J. London, M.D. Anesthesiology July 2024, Vol. 141, A13–A15. Video laryngoscopy vs direct laryngoscopy for endotracheal intubation in the operating room: A cluster randomized clinical trial. JAMA 2024; 331:1279–86. PMID: 38497992 Endotracheal intubation has been traditionally performed in the operating room using direct laryngoscopy. Recently, video laryngoscopy has become widely available. Although it usually […]
Read MoreAuthors: Sandeep G, Kalbande J V, Gupta A, et al. Cureus June 18, 202416(6): e62621. Abstract Bronchogenic cysts (BCs) are a congenital anomaly, forming fluid-filled sacs in the bronchial tree during fetal development, and are relatively rare in adults. Patients with large BCs in the mediastinum presenting with severe tracheal compression pose a significant challenge […]
Read MoreAuthors: Markus Zadrazil, M.D. et al Anesthesiology July 2024, Vol. 141, 24–31. Background Little is known about the pharmacodynamic characteristics of liposomal bupivacaine. Hypothesizing that they would not identify pharmacodynamic differences from plain bupivacaine during the initial period after administration, but would find better long-term pharmacodynamic characteristics, the authors designed a randomized, controlled, triple-blinded, single-center study […]
Read MoreAuthors: Lena Scotto, MD; Natalie Moreland, MD ASA Monitor March 2024, Vol. 88, 35. Individuals over the age of 65 make up the largest proportion of patients seeking surgical care. Advanced age and underlying cognitive disorders are risk factors for the development of cognitive impairment, the most common complication in this age group. Perioperative neurocognitive disorders (PNDs) […]
Read MoreAuthors: Julie Helms, M.D., Ph.D. et al Anesthesiology July 2024, Vol. 141, 75–86. Background Extracorporeal membrane oxygenation (ECMO) is associated with a high risk of bleeding complications. The specific impact of ECMO on fibrinolysis remains unexplored. The objective of the current pilot observational prospective study was to investigate the longitudinal dynamics of fibrinolytic markers—i.e., changes over […]
Read MoreThe central renin-angiotensin system: A genetic pathway, functional decoding, and selective target engagement characterization in humans. Proc Natl Acad Sci U S A 2024; 121:e2306936121. PMID: 38349873. Author: Charles Emala, M.D. Anesthesiology July 2024, Vol. 141, A13–A15. The peripheral renin angiotensin system (RAS) is a well-characterized hormonal system classically understood to regulate cardiovascular and renal functions, […]
Read MoreAuthors: Côme Bureau, M.D., Ph.D. et al Anesthesiology July 2024, Vol. 141, 87–99. Background Data on assessment and management of dyspnea in patients on venoarterial extracorporeal membrane oxygenation (ECMO) for cardiogenic shock are lacking. The hypothesis was that increasing sweep gas flow through the venoarterial extracorporeal membrane oxygenator may decrease dyspnea in nonintubated venoarterial ECMO patients […]
Read MoreAuthors: Ashish Agrawal, MD et al ASA Monitor October 2023, Vol. 87, 35. Delirium is likely the most well-known perioperative cognitive disorder. Delirium, an acute and fluctuating alteration in the level of consciousness and attention, has significant consequences for patients, families, and the health care system. The incidence of delirium is associated with increased mortality, cognitive […]
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