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Uncategorized Published - 29 July, 2024    By - Dr Clemens
Serious maternal complications linked with use of marijuana before and early in pregnancy

Author: Sandee LaMotte CNN More and more people are using marijuana before or during pregnancy to ease nausea, pain, stress and help with sleep. In fact, research found that use has more than doubled in the last two decades. Marijuana use in pregnancy has been linked to such adverse outcomes for the baby as lower birthweight, preterm birth and higher admission rates […]

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Uncategorized Published - 29 July, 2024    By - Dr Clemens
Microglia Promote Inhibitory Synapse Phagocytosis in the Spinal Cord Dorsal Horn and Modulate Pain-Like Behaviors in a Murine Cancer-Induced Bone Pain Model

AUTHORS: Zhang, Zuoxia MD, PhD et al  Anesthesia & Analgesia 139(2):p 411-419, August 2024. BACKGROUND: The microglial activation has been implicated in cancer-induced bone pain. Recent studies have revealed that microglia mediate synaptic pruning in the central nervous system, where the cluster of differentiation 47-signal regulatory protein α (CD47-SIRPα) axis creates a “don’t eat me” signal […]

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Uncategorized Published - 29 July, 2024    By - Dr Clemens
FDA names 4th syringe manufacturer to avoid

Author: Paige Twenter Becker’s Hospital Review After discovering a quality issue with some plastic syringes manufactured in China, the FDA has issued six import alerts to four companies. The agency has told U.S. suppliers, healthcare providers and consumers to avoid plastic syringes from Jiangsu Caina Medical Co., Jiangsu Shenli Medical Production Co., Shanghai Kindly Enterprise Development Group Co. and […]

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Uncategorized Published - 29 July, 2024    By - Dr Clemens
Anesthesiology Residency Developments

Radius Anesthesia Anesthesiology residency programs are essential for training the next generation of anesthesiologists and equipping them with the skills and knowledge necessary to provide safe and effective anesthesia care. Recent developments and news in anesthesiology residency programs highlight evolving trends, innovative training methods, and responses to current healthcare challenges. One of the most significant developments […]

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Uncategorized Published - 29 July, 2024    By - Dr Clemens
A Slow-Exchange Interstitial Fluid Compartment in Volunteers and Anesthetized Patients

AUTHORS: Hahn, Robert G. MD, PhD; Dull, Randal O. MD, PhD Anesthesia & Analgesia 139(2):p 339-348, August 2024. BACKGROUND: Physiological studies suggest that the interstitial space contains 2 fluid compartments, but no analysis has been performed to quantify their sizes and turnover rates. METHODS: Retrospective data were retrieved from 270 experiments where Ringer’s solution of […]

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Uncategorized Published - 26 July, 2024    By - Dr Clemens
Sugammadex-Associated Anaphylaxis: Summary and Proposed Management

Authors: Chia, Pamela A. MD, MS; Wolfe, Michael W. MD Anesthesia & Analgesia 139(2):p 273-277, August 2024. Sugammadex, a modified γ cyclodextrin, was approved by the US Food and Drug Administration (FDA) in 2015 for reversal of steroidal neuromuscular blockade. Used in the perioperative setting for reversal of amino-steroid paralytics, such as rocuronium and vecuronium, […]

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Uncategorized Published - 26 July, 2024    By - Dr Clemens
Feasibility of Focused Cardiac Ultrasound Performed by Trainees During Cesarean Delivery

AUTHORS: Ortner, Clemens M. MS, MD et al  Anesthesia & Analgesia 139(2):p 332-338, August 2024. | BACKGROUND: Anesthesiology experts advocate for formal education in maternal critical care, including the use of focused cardiac ultrasound (FCU) in high-acuity obstetric units. While benefits and feasibility of FCU performed by experts have been well documented, little evidence exists on the […]

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Uncategorized Published - 26 July, 2024    By - Dr Clemens
ACE Question

ASA Monitor July 2024, Vol. 88, 35. Based on the depth of sedation continuum published by ASA, which of the following patient responses is MOST consistent with moderate sedation? (A) Purposeful response to verbal or tactile stimulation (B) Purposeful response only to repeated or painful stimulation (C) Reflex withdrawal following a painful stimulus ASA developed a […]

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Uncategorized Published - 26 July, 2024    By - Dr Clemens
Association of Early Dexmedetomidine Utilization With Clinical Outcomes After Moderate-Severe Traumatic Brain Injury

AUTHORS: Liu, Sunny Yang BA et al Anesthesia & Analgesia 139(2):p 366-374, August 2024. BACKGROUND: Traumatic brain injury (TBI) is an expensive and common public health problem. Management of TBI oftentimes includes sedation to facilitate mechanical ventilation (MV) for airway protection. Dexmedetomidine has emerged as a potential candidate for improved patient outcomes when used for early […]

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Uncategorized Published - 26 July, 2024    By - Dr Clemens
A Spicy New Treatment for Postoperative Pain

Author: J. David Clark, M.D., Ph.D. Anesthesiology August 2024, Vol. 141, 201–203. “[T]his new [capsaicin] prodrug formulation may provide a novel approach to postoperative analgesia resulting from a single local injection that lasts for days.” Image: A. Johnson, Vivo Visuals Studio. Fundamental advancements in our field do not occur every day, so it is particularly exciting […]

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