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AUTHORS: Zhang, Simin MD et al Anesthesia & Analgesia 139(2):p 397-410, August 2024. | BACKGROUND: Ventral tegmental area (VTA) glutamatergic neurons promote wakefulness in the sleep-wake cycle; however, their roles and neural circuit mechanisms during isoflurane (ISO) anesthesia remain unclear. METHODS: Fiber photometry and in vivo electrophysiology were used to observe the changes in neuronal or terminal […]
Read MoreAuthor: Richard Novak The Anesthesia Consultant At the academic medical center where I work, when a physician reaches the age of 74½ years he or she must pass cognitive testing to retain their medical staff privileges. The testing includes a peer-conducted clinical skills assessment by three medical staff members, a comprehensive physical exam, and cognitive […]
Read MoreWe are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]
Read MoreAuthors: Shiri Zarour, MD et al Anesthesiology July 2024. Background Intraoperative hypotension might contribute to the development of postoperative delirium through inadequate cerebral perfusion. However, evidence regarding the association between intraoperative hypotension and postoperative delirium is equivocal. We therefore tested the hypothesis that in patients>70 years having elective non-cardiac surgery, intraoperative hypotension is associated with […]
Read MoreAuthors: Andrew King, MD, MS et al ASA Monitor April 2024, Vol. 88, 33. A family history of deaths under general anesthesia – an unlikely nightmare for the modern anesthesiologist. But for Dr. Jim Villiers, that was a challenge he had to face for his patient in 1960s Melbourne, Australia. Malignant hyperthermia (MH), a topic we […]
Read MoreAuthors: Steven Gayer, MD, MBA, FASA et al ASA Monitor November 2023, Vol. 87, 29. The warning signs are present. In 2023, some medical specialties are reporting the most severe drug shortages in recent memory (asamonitor.pub/3LkTVMd). These trends have sparked fervent discussions among lawmakers, regulators, and the health care community on how best to mitigate drug […]
Read MoreAuthor: Christian S. Guay, MD International Anesthesia Research Society Beverley A. Orser, MD, PhD, FRCPC, FRSC, Chair of the IARS Board of Trustees, opened this year’s Annual Meeting, on Friday, May 17, by acknowledging the diligent work and dedication of the IARS Trustees and staff. She also traced the illustrious history of the IARS and […]
Read MoreAUTHORS: Takei, Yusuke MD, PhD et al Anesthesia & Analgesia 139(2):p 385-396, August 2024. BACKGROUND: Currently, clinical indicators for evaluating endothelial permeability in sepsis are unavailable. Endothelium-derived extracellular vesicles (EDEVs) are emerging as biomarkers of endothelial injury. Platelet endothelial cell adhesion molecule (PECAM) and vascular endothelial (VE)-cadherin are constitutively expressed endothelial intercellular adhesion molecules that regulate […]
Read MoreAuthors: Hongye Zhang, MD et al Anesthesiology July 2024. Background A brachial plexus block plays an important role in providing perioperative analgesia for shoulder surgery; however, the inherent risk of phrenic nerve block and resulting hemidiaphragmatic paralysis may limit its use in patients with compromised pulmonary function. This study aimed to evaluate safety, efficacy, the […]
Read MoreAuthors: Zain Wedemeyer, B.S. et al Anesthesiology August 2024, Vol. 141, 262–271. Background The accuracy and precision of currently available, widely used acceleromyograph and electromyograph neuromuscular blockade monitors have not been well studied. In addition, the normalization of the train-of-four ratio from acceleromyography (train-of-four ratio [T4/T1] divided by the baseline train-of-four ratio) has not been validated […]
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